Asbestos Cancer Attorney - Get What Due You From Your Illness
If you have become sick with cancer for the reason that some business put asbestos into their product, it follows that you want to obtain the assistance of a lawyer. Mostly, folks want justice from those responsible. There is a vast distinction between revenge and justice. Even though some individuals seeking asbestos cancer attorneys begin by having a desire for revenge, ultimately, they might just hope to see justice served. A top asbestos attorney might be able to make certain that those at fault will take the blame of what's happened to you.
Should you decide to take legal action, there's a small possibility that the corporation will win. In the end, in today-s world, money talks. It's furthermore a recognized fact that a trapped individual will fight the hardest. Should you have a corporation by the throat due to what that business did or didn't do, in that case you can be certain that the business will do all in its ability to fight you. You need the expertise of a knowledgeable asbestos cancer attorney to help you.
You must understand how to select the attorney for your requirements. You might know, the quantity of asbestos litigation keeps increasing and some lawyers will simply do anything to obtain a portion of the money concerned. These are some tips when in search of a top asbestos cancer attorney.
You should know how knowledgeable they are before you hire a cancer lawyer. Not the number of years that they have been practicing law but the number of cases they have encountered. Certain lawyers try to make an impression on potential clients by stating how many years they have been an attorney. Don't be fooled by this declaration. What you need to know is how many times has this lawyer come across a case like yours.
A lot of individuals who hire asbestos cancer attorneys are concerned about the expenses that they might encounter. You must discuss fees prior to hiring this type of lawyer. You must also inquire about the numerous fees that you'll come upon throughout the lawsuit. You should be certain that each fee is suitably explained. A lot of folks are confused by the complex words, however if you don't speak up, then you could wind up being tricked. Maybe you believe that your circumstance is too unfortunate to be exploited, however you don't realize just how low some individuals will go for money.
Conversely, you may in fact come across an asbestos cancer attorney whom you trust. You might design a payment plan that won't increase your worries. Actually, many asbestos cancer attorneys these days are agreeable to postpone their fees pending winning the case.
To learn more about finding an somekeyword, try visiting , a health topics website where you can find all kinds of health related information including cancer mesothelioma treatment, heart disease, menopause and more.
Friday, August 31, 2012
The Dangers Of Naturally Occurring Asbestos
NOA: Naturally Occurring Asbestos
Naturally occurring asbestos (NOA) is a relatively recent focus of study and debate. The term "NOA" usually refers to the silicate minerals serpentine and amphibole that are present naturally in rock. If asbestos deposits in the ground or in rock the most common sources of NOA are left undisturbed, they may not present a significant health hazard.
When NOA Is Disturbed
It is when NOA deposits are disturbed that they may give off the carcinogenic fibers that initiate asbestos diseases such as mesothelioma cancer, asbestosis and lung cancer. Among the many ways that a deposit of NOA may be disturbed are:
?Mining
?Quarrying
?Evacuation for the construction of a building
?Farming
?Landscaping
?Gardening
?Shoveling or raking gravel that contains asbestos
?Recreational activities that disturb the soil e.g., ATVs, bicycles, jogging
Regarding the last item, recreational activities, it is known that the trailing members of a group of runners, cyclists or vehicle riders are exposed to much higher levels of toxins in the soil compared to the leaders, and that children may suffer from the asbestos exposure more so than adults.
Naturally Occurring Asbestos in Your Community
If a community has confirmed that one or more naturally occurring asbestos deposits are present within its confines, several issues arise, including:
?Whether to remove the NOA, and how to do so
?How to reconcile the differing interests of residents, scientific experts, commercial interests, government agencies, etc.
?Possible reduction in property values
?Health concerns
?Employment changes
Harmful Affects of Asbestos Exposure
While naturally occurring asbestos mines are not harmful, once disturbed, they become extremely toxic and can lead to the development of asbestos cancers. Asbestos is made up of strands of durable fibers that if broken down, separate, creating a form of dust that can be easily swallowed. If swallowed, the fibers can become embedded in the lungs and over time create irritation, and eventually lead to the development of fatal diseases such as asbestos cancer.
You May be Exposed to Asbestos without Even Knowing It
For more information regarding asbestos exposure, contact us today. Our asbestos attorneys will provide you with helpful information and resources regarding the toxic mineral. You and your family may be exposed to asbestos everyday without even knowing it. Contact us to make sure you are protected.
Naturally occurring asbestos (NOA) is a relatively recent focus of study and debate. The term "NOA" usually refers to the silicate minerals serpentine and amphibole that are present naturally in rock. If asbestos deposits in the ground or in rock the most common sources of NOA are left undisturbed, they may not present a significant health hazard.
When NOA Is Disturbed
It is when NOA deposits are disturbed that they may give off the carcinogenic fibers that initiate asbestos diseases such as mesothelioma cancer, asbestosis and lung cancer. Among the many ways that a deposit of NOA may be disturbed are:
?Mining
?Quarrying
?Evacuation for the construction of a building
?Farming
?Landscaping
?Gardening
?Shoveling or raking gravel that contains asbestos
?Recreational activities that disturb the soil e.g., ATVs, bicycles, jogging
Regarding the last item, recreational activities, it is known that the trailing members of a group of runners, cyclists or vehicle riders are exposed to much higher levels of toxins in the soil compared to the leaders, and that children may suffer from the asbestos exposure more so than adults.
Naturally Occurring Asbestos in Your Community
If a community has confirmed that one or more naturally occurring asbestos deposits are present within its confines, several issues arise, including:
?Whether to remove the NOA, and how to do so
?How to reconcile the differing interests of residents, scientific experts, commercial interests, government agencies, etc.
?Possible reduction in property values
?Health concerns
?Employment changes
Harmful Affects of Asbestos Exposure
While naturally occurring asbestos mines are not harmful, once disturbed, they become extremely toxic and can lead to the development of asbestos cancers. Asbestos is made up of strands of durable fibers that if broken down, separate, creating a form of dust that can be easily swallowed. If swallowed, the fibers can become embedded in the lungs and over time create irritation, and eventually lead to the development of fatal diseases such as asbestos cancer.
You May be Exposed to Asbestos without Even Knowing It
For more information regarding asbestos exposure, contact us today. Our asbestos attorneys will provide you with helpful information and resources regarding the toxic mineral. You and your family may be exposed to asbestos everyday without even knowing it. Contact us to make sure you are protected.
Asbestos Burden In Plaques Compared To Content In Lungs
Asbestos Fibers can be deadly when they broken into tiny pieces and inhaled or swallowed. We must all do our part when it comes to raising public awareness about the terrible diseases associated with asbestos exposure. One interesting study is called, A comparison of asbestos burden in lung parenchyma, lymph nodes, and plaques by Dodson, RF, Williams, MG Jr., Corn, CJ, Brollo, A, and Blanch, C - Annals of the New York Academy of Sciences. Vol. 643, pp. 53-58. 1991. Here is an excerpt: The lack of quantitative studies concerning the asbestos burden in plaques has resulted in the statement that the "asbestos fiber content of plaques and pleura appears to be quite different from that of the lung, and these sites are not useful for mineral analysis." The present study was designed to test this concept. The tissue from occupationally exposed individuals was assessed by light and transmission electron microscopy and the fiber burden, types, and dimensions were recorded. Quantitation of the asbestos burden (ferruginous bodies and uncoated fibers) found in the original site of deposition (lung) was compared with that burden found in relocation sites (lymph nodes and pleura).
A second study is called, Cell signaling pathways elicited by asbestos by B.T. Mossman, S Faux, Y Janssen, L A Jimenez, C Timblin, C Zanella, J Goldberg, E Walsh, A Barchowsky, and K Driscoll - Department of Pathology, University of Vermont College of Medicine, Burlington 05405, USA. - Environ Health Perspect. 1997 September; 105(Suppl 5): 11211125. Here is an excerpt: Abstract - In recent years, it has become apparent that minerals can trigger alterations in gene expression by initiating signaling events upstream of gene transactivation. These cascades may be initiated at the cell surface after interaction of minerals with the plasma membrane either through receptorlike mechanisms or integrins. Alternatively, signaling pathways may be stimulated by active oxygen species generated both during phagocytosis of minerals and by redox reactions on the mineral surface. At least two signaling cascades linked to activation of transcription factors, i.e., DNA-binding proteins involved in modulating gene expression and DNA replication, are stimulated after exposure of lung cells to asbestos fibers in vitro. These include nuclear factor kappa B (NF kappa B) and the mitogen-activated protein kinase (MAPK) cascade important in regulation of the transcription factor, activator protein-1 (AP-1). Both NF kappa B and AP-1 bind to specific DNA sequences within the regulatory or promoter regions of genes that are critical to cell proliferation and inflammation. Unraveling the cell signaling cascades initiated by mineral dusts and pharmacologic inhibition of these events may be important for the control and treatment of mineral-associated occupational diseases.
A third study is called, Ventilatory failure due to asbestos pleurisy by Albert Miller, M.D., Alvin S. Teirstein, M.D., Irving J. Selikoff, M.D.b - Volume 75, Issue 6, Pages 911-919 (December 1983). Here is an excerpt: Abstract - Seven patients are described who had a distinctive syndrome of chest wall restriction caused by asbestos-induced pleural fibrosis. All had severe dyspnea and predominant pleural disease on radiographic examination, with pulmonary function findings of reduced vital capacity, total lung capacity (measured in five patients), and maximal voluntary ventilation. Five patients had ventilatory failure with carbon dioxide retention; four of these have died and one is close to death. Examination of the thoracic organs in five patients showed minimal or no parenchymal fibrosis in three and less severe involvement of the parenchyma than of the pleura in the remaining two. Neoplasms were suspected in three patients because of extension of the pleural fibrosis into the lung. Two of these patients had pleural uptake of 67-gallium citrate attributable to the inflammatory reaction. With the increasing duration since onset of exposure in the nine million workers who have been exposed to asbestos, as well as in other exposed persons, it is expected that additional cases of ventilatory failure caused by asbestos-induced pleural fibrosis will be encountered.
If you found any of these studies interesting, please read them in their entirety. We all owe a great deal of thanks to the people who are researching these important issues.
A second study is called, Cell signaling pathways elicited by asbestos by B.T. Mossman, S Faux, Y Janssen, L A Jimenez, C Timblin, C Zanella, J Goldberg, E Walsh, A Barchowsky, and K Driscoll - Department of Pathology, University of Vermont College of Medicine, Burlington 05405, USA. - Environ Health Perspect. 1997 September; 105(Suppl 5): 11211125. Here is an excerpt: Abstract - In recent years, it has become apparent that minerals can trigger alterations in gene expression by initiating signaling events upstream of gene transactivation. These cascades may be initiated at the cell surface after interaction of minerals with the plasma membrane either through receptorlike mechanisms or integrins. Alternatively, signaling pathways may be stimulated by active oxygen species generated both during phagocytosis of minerals and by redox reactions on the mineral surface. At least two signaling cascades linked to activation of transcription factors, i.e., DNA-binding proteins involved in modulating gene expression and DNA replication, are stimulated after exposure of lung cells to asbestos fibers in vitro. These include nuclear factor kappa B (NF kappa B) and the mitogen-activated protein kinase (MAPK) cascade important in regulation of the transcription factor, activator protein-1 (AP-1). Both NF kappa B and AP-1 bind to specific DNA sequences within the regulatory or promoter regions of genes that are critical to cell proliferation and inflammation. Unraveling the cell signaling cascades initiated by mineral dusts and pharmacologic inhibition of these events may be important for the control and treatment of mineral-associated occupational diseases.
A third study is called, Ventilatory failure due to asbestos pleurisy by Albert Miller, M.D., Alvin S. Teirstein, M.D., Irving J. Selikoff, M.D.b - Volume 75, Issue 6, Pages 911-919 (December 1983). Here is an excerpt: Abstract - Seven patients are described who had a distinctive syndrome of chest wall restriction caused by asbestos-induced pleural fibrosis. All had severe dyspnea and predominant pleural disease on radiographic examination, with pulmonary function findings of reduced vital capacity, total lung capacity (measured in five patients), and maximal voluntary ventilation. Five patients had ventilatory failure with carbon dioxide retention; four of these have died and one is close to death. Examination of the thoracic organs in five patients showed minimal or no parenchymal fibrosis in three and less severe involvement of the parenchyma than of the pleura in the remaining two. Neoplasms were suspected in three patients because of extension of the pleural fibrosis into the lung. Two of these patients had pleural uptake of 67-gallium citrate attributable to the inflammatory reaction. With the increasing duration since onset of exposure in the nine million workers who have been exposed to asbestos, as well as in other exposed persons, it is expected that additional cases of ventilatory failure caused by asbestos-induced pleural fibrosis will be encountered.
If you found any of these studies interesting, please read them in their entirety. We all owe a great deal of thanks to the people who are researching these important issues.
Thursday, August 30, 2012
The Deadly Health Hazard Of Asbestos
Asbestos is a term used for some naturally occurring minerals that form long thin fibers and fiber bundles on crystallization. Most commonly found group is the serpentine group that includes Chrysotile (white asbestos). It is also the most frequently mined form of Asbestos. Another very important asbestos group is known as the amphiboles, which includes Crocidolite (blue asbestos) and Amosite (brown asbestos). The asbestos fibers have high tensile strength, and chemical, electrical and heat resistance properties and so are extremely useful as a building/insulation material. Asbestos has been used extensively all over the world.
Asbestos: General Information
Although Asbestos is a hazardous material, it poses a health risk only if the Asbestos fibers become airborne and subsequently inhaled. Therefore, most Asbestos materials pose little health risk unless they are disturbed in a way that allows the fibers to be released into the atmosphere. Inhalation of asbestos fibers can lead to serious diseases such as lung cancer, Mesothelioma (a cancer of the lining of the lungs or lower digestive tract) and asbestosis (a chronic fibrosis of the lungs).
Many industries used Asbestos extensively in the past, exposing their workers to this deadly materials. As a result, many new cases of Asbestos caused ailments are occurring now. However, the fact that Asbestos was also installed in many buildings means that a wider range of people still have the potential to be exposed - particularly building and maintenance workers. For this reason, the latest revision of the Control of Asbestos at Work Regulations introduces (from May 2004) a new responsibility on those responsible for non-domestic premises to manage the asbestos contained in them.
Asbestos Caused Diseases
Mesothelioma is a cancer of the pleural and peritoneal lining. It exclusively related to asbestos exposure. By the time it is diagnosed, it is usually fatal. Mesothelioma has a long latency period (time between exposure and onset of disease) of at least 15 years and sometimes as long as 60 years.
Asbestosis is a scarring of the lung tissue. This scarring impairs the elasticity of the lung and hampers its ability to exchange gases. This leads to inadequate oxygen intake to the blood. Asbestosis restricts breathing leading to decreased lung volume and increased resistance in the airways. It is a slowly progressive disease with a latency period of 15 to 30 years.
Lung Cancer is a malignant tumor of the bronchi covering. The tumor grows through surrounding tissue, invading and often obstructing air passages. Again, the disease has a long latency period of at least 20 years.
The victims of all these asbestos related diseases are eligible to file lawsuits for compensation against the persons and organizations responsible for causing asbestos exposure. They can take the help of mesothelioma and asbestos attorneys to fight their compensation claims.
Asbestos: General Information
Although Asbestos is a hazardous material, it poses a health risk only if the Asbestos fibers become airborne and subsequently inhaled. Therefore, most Asbestos materials pose little health risk unless they are disturbed in a way that allows the fibers to be released into the atmosphere. Inhalation of asbestos fibers can lead to serious diseases such as lung cancer, Mesothelioma (a cancer of the lining of the lungs or lower digestive tract) and asbestosis (a chronic fibrosis of the lungs).
Many industries used Asbestos extensively in the past, exposing their workers to this deadly materials. As a result, many new cases of Asbestos caused ailments are occurring now. However, the fact that Asbestos was also installed in many buildings means that a wider range of people still have the potential to be exposed - particularly building and maintenance workers. For this reason, the latest revision of the Control of Asbestos at Work Regulations introduces (from May 2004) a new responsibility on those responsible for non-domestic premises to manage the asbestos contained in them.
Asbestos Caused Diseases
Mesothelioma is a cancer of the pleural and peritoneal lining. It exclusively related to asbestos exposure. By the time it is diagnosed, it is usually fatal. Mesothelioma has a long latency period (time between exposure and onset of disease) of at least 15 years and sometimes as long as 60 years.
Asbestosis is a scarring of the lung tissue. This scarring impairs the elasticity of the lung and hampers its ability to exchange gases. This leads to inadequate oxygen intake to the blood. Asbestosis restricts breathing leading to decreased lung volume and increased resistance in the airways. It is a slowly progressive disease with a latency period of 15 to 30 years.
Lung Cancer is a malignant tumor of the bronchi covering. The tumor grows through surrounding tissue, invading and often obstructing air passages. Again, the disease has a long latency period of at least 20 years.
The victims of all these asbestos related diseases are eligible to file lawsuits for compensation against the persons and organizations responsible for causing asbestos exposure. They can take the help of mesothelioma and asbestos attorneys to fight their compensation claims.
Rhode Island Demolition Co. Fined For Asbestos Violations
Violations of the National Emission Standard for Hazardous Air Pollutants for Asbestos (Asbestos NESHAP) and the federal Clean Air Act (CAA) are the basis of a $256,320 fine for the Johnston, Rhode Island company Bilray Demolition, Inc. The U.S. Environmental Protection Agency (EPA) levied the fine against Bilray for its demolition of the Seaboard Foundry in R.I. in 2004 and 2005.
Violations of Asbestos Removal/Disposal Procedures
The demolition was performed after a fire at the foundry. According to the EPA, Bilray Demolition:
* did not properly inspect the foundry for asbestos before it began the demolition
* did not provide the required written notice of its intended demolition to the EPA before beginning the work
* failed to implement the correct safety procedures for removing asbestos or for disposing of the asbestos; e.g., they failed to keep asbestos adequately wet until it was collected
Asbestos abatement was eventually conducted at the foundry by Bilray. Approximately 81 cubic feet of asbestos-containing materials were removed from the foundry in September 2005 by Bilray.
The Laws Exist to Protect People from Exposure to Toxins
The owners and operators of demolition and renovation companies in the U.S. are required to follow the relevant laws (i.e., the NESHAP, the CAA and others) so that their employees and the residents of the communities in which the demolished or renovated structures are located are not exposed to toxic levels of asbestos and other hazardous materials.
Asbestos exposure can cause respiratory disease such as asbestosis, and cancer such as mesothelioma (cancer of a tissue lining in the chest cavity) and lung malignancies. Millions of buildings across the U.S. including private residences and factories have literally hundreds of asbestos containing components. The removal of such asbestos construction materials should usually be left to professionals, and these professionals should follow the state and federal laws.
(Source: EPA)
Do you need legal help?
If you and your family have been exposed to a dangerous level of asbestos, contact mesothelioma treatment centers to speak with a knowledgeable asbestos attorney who will help you obtain financial compensation for your medical bills and losses.
Violations of Asbestos Removal/Disposal Procedures
The demolition was performed after a fire at the foundry. According to the EPA, Bilray Demolition:
* did not properly inspect the foundry for asbestos before it began the demolition
* did not provide the required written notice of its intended demolition to the EPA before beginning the work
* failed to implement the correct safety procedures for removing asbestos or for disposing of the asbestos; e.g., they failed to keep asbestos adequately wet until it was collected
Asbestos abatement was eventually conducted at the foundry by Bilray. Approximately 81 cubic feet of asbestos-containing materials were removed from the foundry in September 2005 by Bilray.
The Laws Exist to Protect People from Exposure to Toxins
The owners and operators of demolition and renovation companies in the U.S. are required to follow the relevant laws (i.e., the NESHAP, the CAA and others) so that their employees and the residents of the communities in which the demolished or renovated structures are located are not exposed to toxic levels of asbestos and other hazardous materials.
Asbestos exposure can cause respiratory disease such as asbestosis, and cancer such as mesothelioma (cancer of a tissue lining in the chest cavity) and lung malignancies. Millions of buildings across the U.S. including private residences and factories have literally hundreds of asbestos containing components. The removal of such asbestos construction materials should usually be left to professionals, and these professionals should follow the state and federal laws.
(Source: EPA)
Do you need legal help?
If you and your family have been exposed to a dangerous level of asbestos, contact mesothelioma treatment centers to speak with a knowledgeable asbestos attorney who will help you obtain financial compensation for your medical bills and losses.
Wednesday, August 29, 2012
Prevention Of Asbestos Related Death
Promoting awareness about mesothelioma and the links to asbestos exposure is very important. Especially considering the fact that there are many people out there trying to misinform the public. Some measurements put the number of people who have died because of asbestos poisoning or exposure at over a quarter million. That is a truly staggering number. The good news is many doctors and researchers are working feverishly to try to find a cure and learn more. Every day new research and clinic trial are being done to combat this deadly disease. We should all do out part in trying to get the word out.
One interesting study is called, Asbestos Fibres in Beverages and Drinking Water - Nature 232, 332 - 333 (30 July 1971); by H. M. CUNNINGHAM & R. PONTEFRACT - Food and Drug Directorate, Department of Health and Welfare, Ottawa.
Here is an excerpt: THE hazards of inhaling asbestos fibres1-4, the high incidence of gastrointestinal cancer1,2,5-7 and abdominal neoplasms3,8,9 among asbestos workers and the fact that asbestos fibres may penetrate the mucosa of the stomach and the intestine of animals10,11 are known and so it is important to study the distribution of asbestos fibres in the environment. Asbestos fibres have already been found in beer12, and the occurrence of fibres 0.5 nm in length and 0.01 nm in diameter suggests that such material may find its way through filtering systems into city drinking water supplies, and this we have been able to confirm.
Another interesting study is called, Prevention of asbestos-induced cell death in rat lung fibroblasts and alveolar macrophages by scavengers of active oxygen species by Shatos, M.A. ; Doherty, J.M. ; Marsh, J.P.; and Mossman, B.T. - Publication Date 1987 Oct 01 Resource Relation Journal Name: Environ. Res.; (United States); Journal Volume: 44:1 - Research Org Univ. of Vermont College of Medicine, Burlington. Here is an excerpt: The possible modulation of asbestos-related cell death using antioxidants in both target and effector cells of asbestosis was investigated. After exposure to crocidolite asbestos at a range of concentrations (2.5-25 ..mu..gcm/sup 2/ dish), the viability of a normal rat lung fibroblast line and freshly isolated alveolar macrophages (AM) was determined. In comparison to fibroblasts, AM were more resistant to the cytotoxic effects of asbestos. Cytotoxic concentrations of asbestos then were added to both cell types in combination with the antioxidants, superoxide dismutase (SOD), a scavenger of superoxide (O/sub 2//sup -./), and catalase, an enzyme scavenging H/sub 2/O/sub 2/. Dimethylthiourea (DMTU), a scavenger of the hydroxyl radical (OH/sup ./) and deferoxamine, an iron chelator, also were evaluated in similar studies. Results showed significant dosage-dependent reduction of asbestos-associated cell death with all agents. In contrast, asbestos-induced toxicity was not ameliorated after addition of chemically inactivated SOD and catalase or bovine serum albumin. Results above suggest asbestos-induced cell damage is mediated by active oxygen species. In this regard, the iron associated with the fiber andor its interaction with cell membranes might be critical in deriving a modified Haber-Weiss (Fenton-type) reaction resulting in production of OH/sup ./.
If you found either of these excerpts interesting, please read the studies in their entirety. Additionally, please do your part to try and raise awareness about mesothelioma. This article should not be construed as legal nor medical advice.
One interesting study is called, Asbestos Fibres in Beverages and Drinking Water - Nature 232, 332 - 333 (30 July 1971); by H. M. CUNNINGHAM & R. PONTEFRACT - Food and Drug Directorate, Department of Health and Welfare, Ottawa.
Here is an excerpt: THE hazards of inhaling asbestos fibres1-4, the high incidence of gastrointestinal cancer1,2,5-7 and abdominal neoplasms3,8,9 among asbestos workers and the fact that asbestos fibres may penetrate the mucosa of the stomach and the intestine of animals10,11 are known and so it is important to study the distribution of asbestos fibres in the environment. Asbestos fibres have already been found in beer12, and the occurrence of fibres 0.5 nm in length and 0.01 nm in diameter suggests that such material may find its way through filtering systems into city drinking water supplies, and this we have been able to confirm.
Another interesting study is called, Prevention of asbestos-induced cell death in rat lung fibroblasts and alveolar macrophages by scavengers of active oxygen species by Shatos, M.A. ; Doherty, J.M. ; Marsh, J.P.; and Mossman, B.T. - Publication Date 1987 Oct 01 Resource Relation Journal Name: Environ. Res.; (United States); Journal Volume: 44:1 - Research Org Univ. of Vermont College of Medicine, Burlington. Here is an excerpt: The possible modulation of asbestos-related cell death using antioxidants in both target and effector cells of asbestosis was investigated. After exposure to crocidolite asbestos at a range of concentrations (2.5-25 ..mu..gcm/sup 2/ dish), the viability of a normal rat lung fibroblast line and freshly isolated alveolar macrophages (AM) was determined. In comparison to fibroblasts, AM were more resistant to the cytotoxic effects of asbestos. Cytotoxic concentrations of asbestos then were added to both cell types in combination with the antioxidants, superoxide dismutase (SOD), a scavenger of superoxide (O/sub 2//sup -./), and catalase, an enzyme scavenging H/sub 2/O/sub 2/. Dimethylthiourea (DMTU), a scavenger of the hydroxyl radical (OH/sup ./) and deferoxamine, an iron chelator, also were evaluated in similar studies. Results showed significant dosage-dependent reduction of asbestos-associated cell death with all agents. In contrast, asbestos-induced toxicity was not ameliorated after addition of chemically inactivated SOD and catalase or bovine serum albumin. Results above suggest asbestos-induced cell damage is mediated by active oxygen species. In this regard, the iron associated with the fiber andor its interaction with cell membranes might be critical in deriving a modified Haber-Weiss (Fenton-type) reaction resulting in production of OH/sup ./.
If you found either of these excerpts interesting, please read the studies in their entirety. Additionally, please do your part to try and raise awareness about mesothelioma. This article should not be construed as legal nor medical advice.
Upper Lobe Tumors And Asbestos Exposure
Over 2,000 new cases of Mesothelioma are diagnosed each year in the United States (making up about 3 % of all cancer diagnoses). The more research that is dedicated to finding a cure for this disease, the better. One interesting study is called, A Meta-Analysis of Colorectal Cancer and Asbestos Exposure by David M. Horna, David H. Garabrant, and Brenda W. Gillespie - American Journal of Epidemiology Vol. 139, No. 12: 1210-1222. Here is an excerpt: A meta-analysis of the relation between asbestos exposure and colorectal cancer mortality was conducted, using published reports of 20 asbestos-exposed cohorts. Summary standardized mortality ratios (SMRs) for colorectal cancer were examined in relation to asbestos type and estimates of dust exposure (as direct estimators of asbestos exposure) and in relation to lung cancer SMR and the proportion of all deaths due to mesothelioma (as proxy estimators of asbestos exposure). An elevated summary SMR was observed in cohorts exposed to amphibole asbestos (summary SMR = 1.47; 95% confidence interval (Cl) 1.092.00), but not in cohorts exposed to serpentine asbestos (summary SMR = 1.04; 95% Cl 0.811.33) or in cohorts exposed to both serpentine and amphibole asbestos (summary SMR = 1.03; 95% Cl 0.741.42). Cohorts having a lung cancer SMR greater than 2.00 had a summary SMR of 1.51 (95% Cl 1.291.76), and cohorts in which more than 1 % of all deaths were attributed to mesothelioma had a summary SMR of 1.24 (95% Cl 0.941.64), After stratifying the cohorts based on mortality due to all cancers excluding those known or suspected to be associated with asbestos exposure, lung cancer mortality was not clearly associated with colorectal cancer mortality, suggesting that the crude association between these factors may be due to misdiagnosis of lung cancer as other types of cancer in the reported causes of death. These results suggest that exposure to amphibole asbestos may be associated with colorectal cancer, but these findings may reflect an artifact of miscertification of cause of death. The results also suggest that serpentine asbestos is not associated with colorectal cancer.
A second study is called, Association of Cigarette Smoking and Asbestos Exposure with Location and Histology of Lung Cancer by BURTON W. LEE, JOHN C. WAIN, KARL T. KELSEY, JOHN K. WIENCKE, and DAVID C. CHRISTIANI - Am. J. Respir. Crit. Care Med., Volume 157, Number 3, March 1998, 748-755. Here is an excerpt: Prior studies have suggested that lung cancers that arise in association with cigarette smoking favor an upper-lobe location while those associated with asbestos exposure favor a lower-lobe location. An excess of adenocarcinomas has also been reported among cases not exposed to cigarette smoke as well as among those exposed to asbestos. However, these studies typically have not adjusted adequately for potential confounders such as the patient's age, sex, race, or family history of cancer. To better examine the effects of cigarette smoking and asbestos exposure on location and histology of lung cancer, we analyzed data from a large case-control study that included 456 patients with stage I or II lung cancer. Patients with upper-lobe tumors tended to have had more exposure to tobacco as assessed by pack-years smoked (54.7 versus 46.2, p = 0.07) and less time since quitting smoking (3.0 versus 5.5 yr, p = 0.05). In contrast to some prior reports, asbestos exposure was also associated with an upper-lobe location of tumor. Among those with upper-lobe tumors, 14.6% had a history of significant asbestos exposure compared with 5.4% of those with lower-lobe tumors (p
If you found any of these studies interesting, please read them in their entirety. We all owe a great deal of thanks to the people who are researching these important issues.
A second study is called, Association of Cigarette Smoking and Asbestos Exposure with Location and Histology of Lung Cancer by BURTON W. LEE, JOHN C. WAIN, KARL T. KELSEY, JOHN K. WIENCKE, and DAVID C. CHRISTIANI - Am. J. Respir. Crit. Care Med., Volume 157, Number 3, March 1998, 748-755. Here is an excerpt: Prior studies have suggested that lung cancers that arise in association with cigarette smoking favor an upper-lobe location while those associated with asbestos exposure favor a lower-lobe location. An excess of adenocarcinomas has also been reported among cases not exposed to cigarette smoke as well as among those exposed to asbestos. However, these studies typically have not adjusted adequately for potential confounders such as the patient's age, sex, race, or family history of cancer. To better examine the effects of cigarette smoking and asbestos exposure on location and histology of lung cancer, we analyzed data from a large case-control study that included 456 patients with stage I or II lung cancer. Patients with upper-lobe tumors tended to have had more exposure to tobacco as assessed by pack-years smoked (54.7 versus 46.2, p = 0.07) and less time since quitting smoking (3.0 versus 5.5 yr, p = 0.05). In contrast to some prior reports, asbestos exposure was also associated with an upper-lobe location of tumor. Among those with upper-lobe tumors, 14.6% had a history of significant asbestos exposure compared with 5.4% of those with lower-lobe tumors (p
If you found any of these studies interesting, please read them in their entirety. We all owe a great deal of thanks to the people who are researching these important issues.
Tuesday, August 28, 2012
Tulsa Mesothelioma Attorneys -let Them Fight For You!
Mesothelioma is an uncommon but deadly cancer caused by prolonged exposure to asbestos. It is caused by the inhalation of asbestos dust and particles. When inhaled, asbestos fibers adhere to the lining membrane of several vital organs, mainly the lungs and the abdomen.
Competent Tulsa mesothelioma attorneys and lawyers can give you all the legal assistance that you will need in your asbestos related lawsuit. This cancer usually take up to two decades to develop after exposure to asbestos. Often times, once a person has been diagnosed with this deadly diseased, they have only a short time to live. Because of this, it is extremely important that you seek legal representation by a professional Tulsa mesothelioma attorney as soon as your diagnosis has been confirmed. Your attorney will need time to prepare your case to give you the best possible chance of getting compensation for your pain and suffering.
Tulsa Mesothelioma Lawyers Tulsa mesothelioma lawyers can help you and your loved ones get the compensation you deserve for your pain and suffering. In the 1980's it became a widely known fact that exposure to airborne asbestos fibers and dust could cause serious health issues. Respiratory problems and scarring of the lungs could be caused by exposure to asbestos, and, more notably mesothelioma, a form of cancer can also develop.
It usually takes decades after exposure to asbestos before the symptoms of the cancer start appearing However once the symptoms appear it means that the victim has but only few months left to live. There is legal assistance available for sufferers in the Tulsa area in the form of a Tulsa mesothelioma attorney or lawyer. Here are examples of Tulsa Oklahoma mesothelioma Lawyers:
-Michael R bilbery Law offices PC www.bilberylawoffice.com
-Cooney &Conway www.cooneyconway.com
-HartLaw office PC www.hartlawofficepc.com
-Find Law Legal connection www.Legalconnection.com
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Competent Tulsa mesothelioma attorneys and lawyers can give you all the legal assistance that you will need in your asbestos related lawsuit. This cancer usually take up to two decades to develop after exposure to asbestos. Often times, once a person has been diagnosed with this deadly diseased, they have only a short time to live. Because of this, it is extremely important that you seek legal representation by a professional Tulsa mesothelioma attorney as soon as your diagnosis has been confirmed. Your attorney will need time to prepare your case to give you the best possible chance of getting compensation for your pain and suffering.
Tulsa Mesothelioma Lawyers Tulsa mesothelioma lawyers can help you and your loved ones get the compensation you deserve for your pain and suffering. In the 1980's it became a widely known fact that exposure to airborne asbestos fibers and dust could cause serious health issues. Respiratory problems and scarring of the lungs could be caused by exposure to asbestos, and, more notably mesothelioma, a form of cancer can also develop.
It usually takes decades after exposure to asbestos before the symptoms of the cancer start appearing However once the symptoms appear it means that the victim has but only few months left to live. There is legal assistance available for sufferers in the Tulsa area in the form of a Tulsa mesothelioma attorney or lawyer. Here are examples of Tulsa Oklahoma mesothelioma Lawyers:
-Michael R bilbery Law offices PC www.bilberylawoffice.com
-Cooney &Conway www.cooneyconway.com
-HartLaw office PC www.hartlawofficepc.com
-Find Law Legal connection www.Legalconnection.com
-
Iron Workers Asbestos Materials And The Mesothelioma Menace
One group that has been profoundly impacted by asbestos are iron workers. In fact, they have one of the highest rates of mesothelioma of any trade group because the use of asbestos was so ubiquitous during their work day. Exposure resulted in a variety of ways. Workers could inhale asbestos paint that was sprayed onto the iron beams. They could also inhale asbestos dust during sanding or drilling. Even some of their clothing was made from asbestos materials.
If we are ever going to find a cure for mesothelioma or lung cancer, we are going to need to fully fund medical research and raise public awareness. One interesting study is called, Asbestos, chromosomal deletions, and tumor suppressor gene alterations in human malignant mesothelioma by Siva S. Murthy, and Joseph R. Testa - Program of Molecular Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania. Funded by: National Cancer Institute; Grant Number: CA-45745, CA-06927 - Commonwealth of Pennsylvania. Here is an excerpt: Abstract - Exposure to the carcinogen asbestos is considered to be a major factor contributing to the development of most malignant mesotheliomas (MMs). We highlight the role of asbestos in MM and summarize cytogenetic and molecular genetic findings in this malignancy.
The accumulation of numerous clonal chromosomal deletions in most MMs suggests a multistep process of tumorigenesis, characterized by the loss and/or inactivation of multiple tumor suppressor genes (TSGs). Cytogenetic and loss of heterozygosity (LOH) analyses of MMs have demonstrated frequent deletions of specific sites within chromosome arms 1p, 3p, 6q, 9p, 13q, 15q, and 22q. Furthermore, TSGs within two of these regions, i.e., p16/CDKN2A-p14ARF at 9p21 and NF2 at 22q12, are frequently altered in MMs. Homozygous deletion appears to be the major mechanism affecting p16/CDKN2A-p14ARF, whereas inactivating mutations coupled with allelic loss occur at the NF2 locus. Finally, recent studies have demonstrated the presence and expression of simian virus 40 (SV40) in many MMs. SV40 large T antigen has been shown to inactivate the TSG products Rb and p53, suggesting the possibility that asbestos and SV40 could act as cocarcinogens in MM. The frequent occurrence of homozygous deletions of p16/CDKN2A-p14ARF and the ability of SV40 Tag to bind TSG products suggest that perturbations of both Rb- and p53-dependent growth-regulatory pathways are critically involved in the pathogenesis of MM. J. Cell. Physiol. 180:150-157, 1999. 1999 Wiley-Liss, Inc.
Another interesting study is called, Asbestos induces selective release of lysosomal enzymes from mononuclear phagocytes by Philip Davies, Anthony C. Allison, Jill Ackerman, Ann Butterfield and Susan Williams. - Division of Cell Pathology, MRC Clinical Research Centre, Watford Road, Harrow, Middlesex HA1 3UJ, UK. Here is an excerpt: THE association of asbestos inhalation and lung disease has been recognised for many years1. Asbestosis is a chronic inflammatory reaction in the terminal bronchioles and alveoli of the lung with considerable fibrosis leading to distortion and eventual obliteration of the alveoli. There is also an association between asbestosis and the development of bronchogenic cancer2 and Wagner et al. 3 have noted the occurrence of diffuse pleural and peritoneal mesotheliomas in individuals occupationally exposed to asbestos dust and in experimental animals following intrapleural injection of asbestos.
If you found either of these excerpts helpful, please read them in their entirety.
If we are ever going to find a cure for mesothelioma or lung cancer, we are going to need to fully fund medical research and raise public awareness. One interesting study is called, Asbestos, chromosomal deletions, and tumor suppressor gene alterations in human malignant mesothelioma by Siva S. Murthy, and Joseph R. Testa - Program of Molecular Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania. Funded by: National Cancer Institute; Grant Number: CA-45745, CA-06927 - Commonwealth of Pennsylvania. Here is an excerpt: Abstract - Exposure to the carcinogen asbestos is considered to be a major factor contributing to the development of most malignant mesotheliomas (MMs). We highlight the role of asbestos in MM and summarize cytogenetic and molecular genetic findings in this malignancy.
The accumulation of numerous clonal chromosomal deletions in most MMs suggests a multistep process of tumorigenesis, characterized by the loss and/or inactivation of multiple tumor suppressor genes (TSGs). Cytogenetic and loss of heterozygosity (LOH) analyses of MMs have demonstrated frequent deletions of specific sites within chromosome arms 1p, 3p, 6q, 9p, 13q, 15q, and 22q. Furthermore, TSGs within two of these regions, i.e., p16/CDKN2A-p14ARF at 9p21 and NF2 at 22q12, are frequently altered in MMs. Homozygous deletion appears to be the major mechanism affecting p16/CDKN2A-p14ARF, whereas inactivating mutations coupled with allelic loss occur at the NF2 locus. Finally, recent studies have demonstrated the presence and expression of simian virus 40 (SV40) in many MMs. SV40 large T antigen has been shown to inactivate the TSG products Rb and p53, suggesting the possibility that asbestos and SV40 could act as cocarcinogens in MM. The frequent occurrence of homozygous deletions of p16/CDKN2A-p14ARF and the ability of SV40 Tag to bind TSG products suggest that perturbations of both Rb- and p53-dependent growth-regulatory pathways are critically involved in the pathogenesis of MM. J. Cell. Physiol. 180:150-157, 1999. 1999 Wiley-Liss, Inc.
Another interesting study is called, Asbestos induces selective release of lysosomal enzymes from mononuclear phagocytes by Philip Davies, Anthony C. Allison, Jill Ackerman, Ann Butterfield and Susan Williams. - Division of Cell Pathology, MRC Clinical Research Centre, Watford Road, Harrow, Middlesex HA1 3UJ, UK. Here is an excerpt: THE association of asbestos inhalation and lung disease has been recognised for many years1. Asbestosis is a chronic inflammatory reaction in the terminal bronchioles and alveoli of the lung with considerable fibrosis leading to distortion and eventual obliteration of the alveoli. There is also an association between asbestosis and the development of bronchogenic cancer2 and Wagner et al. 3 have noted the occurrence of diffuse pleural and peritoneal mesotheliomas in individuals occupationally exposed to asbestos dust and in experimental animals following intrapleural injection of asbestos.
If you found either of these excerpts helpful, please read them in their entirety.
Monday, August 27, 2012
Fiber Internalization And Mesothelial Cells
Exposure to hazardous asbestos can be lethal. There are a myriad of studies that investigate the links between exposure and disease development. One interesting study is called, Vitronectin enhances internalization of crocidolite asbestos by rabbit pleural mesothelial cells via the integrin alpha v beta by A. M. Boylan, D. A. Sanan, D Sheppard, and V. C. Broaddus - Department of Medicine, San Francisco General Hospital, California 94110, USA - J Clin Invest. 1995 October; 96(4): 19872001. Here is an excerpt: Abstract - The mechanism by which pleural mesothelial cells, the likely progenitor cells of asbestos-induced mesothelioma, recognize and internalize crocidolite asbestos is unknown. Because incubation of asbestos fibers with serum increases their association with cells, we asked whether a protein coat on asbestos increased internalization of fibers via specific cellular receptors. Coating crocidolite with citronectin, but not with fibronectin or other proteins, increased fiber internalization by rabbit pleural mesothelial cells, as measured by a new technique using fluorescence confocal microscopy. Receptors for vitronectin, alpha v beta 3 and alpha v beta 5, were identified on mesothelial cells. Inhibiting vitronectin receptors by plating cells on a vitronectin substrate or incubating cells with excess soluble vitronectin reduced internalization of vitronectin-coated crocidolite. Inhibition of alpha v beta 5, but not alpha v beta 3, with blocking antibodies similarly reduced internalization. In addition, alpha v beta 5, but not alpha v beta 3, showed immunocytochemical colocalization with fibers. Of biologic relevance, coating crocidolite with serum also increased internalization via alpha v beta 5, an effect dependent on the vitronectin in serum. We conclude that pleural mesothelial cells recognize and internalize vitronectin- and serum-coated asbestos via the integrin alpha v beta 5. Since integrins initiate some of the same signaling pathways as does asbestos, our findings may provide insights into the mechanisms of asbestos-induced biologic effects.
A second study is called, The epidemiology of Mesothelioma by Mark Britton - Volume 29, Issue 1, Pages 18-25 (February 2002) - seminars in oncology. Here is an excerpt: Abstract - It has been more than 40 years since occupational crocidolite exposure in South African miners was found to be associated with development of malignant mesothelial tumors 30 to 40 years later. Similar cases were not seen in the amosite and chrysotile miners. Since then, epidemiological and toxicological knowledge have increased enormously, but mortality continues to rise steeply (5% to 10% per year) in most industrialized countries. Even with widespread asbestos abatement efforts, this increase is likely to continue in Western Europe and the United State well into the next century, at least until 2020. Unregulated use of asbestos in less industrialized countries may cause the epidemic to continue throughout the next century in those regions. Asbestos abatement seems to be successful as evidenced by a decline in the proportion of patients with peritoneal tumors, which are the most common malignancies in heavily exposed individuals. Whereas in the 1960s peritoneal tumors comprised up to 30% of the total, in recent years the proportion has fallen to about 10%, This changing ratio could also be due to the steady increase in pleural tumors. The difficulty in formulating the connection as to the etiology of mesothelioma resulted from an unforeseeable difference in the carcinogenicity of various asbestos and mineral fiber types and was compounded by the very long latency of the disease. Unfortunately, the use of a single term, asbestos, to describe at least five fibrous silicate minerals, each with unique physical, chemical, and biological properties and not infrequently and naturally admixed, severely hampered scientific investigation into the occupational health risks. The field became confused and filled with debate. At the heart of the fiber type controversy lies a fundamentally differing view of the importance of biopersistence of various asbestos fibers in carcinogenesis. This review will deal with the epidemiology of mesothelioma with particular attention to the studies that elucidate the impact of various asbestos fiber types on the etiology of the disease. Semin Oncol 29:18-25.
If you found any of these studies interesting, please read them in their entirety. We all owe a great deal of thanks to the people who are researching these important issues.
A second study is called, The epidemiology of Mesothelioma by Mark Britton - Volume 29, Issue 1, Pages 18-25 (February 2002) - seminars in oncology. Here is an excerpt: Abstract - It has been more than 40 years since occupational crocidolite exposure in South African miners was found to be associated with development of malignant mesothelial tumors 30 to 40 years later. Similar cases were not seen in the amosite and chrysotile miners. Since then, epidemiological and toxicological knowledge have increased enormously, but mortality continues to rise steeply (5% to 10% per year) in most industrialized countries. Even with widespread asbestos abatement efforts, this increase is likely to continue in Western Europe and the United State well into the next century, at least until 2020. Unregulated use of asbestos in less industrialized countries may cause the epidemic to continue throughout the next century in those regions. Asbestos abatement seems to be successful as evidenced by a decline in the proportion of patients with peritoneal tumors, which are the most common malignancies in heavily exposed individuals. Whereas in the 1960s peritoneal tumors comprised up to 30% of the total, in recent years the proportion has fallen to about 10%, This changing ratio could also be due to the steady increase in pleural tumors. The difficulty in formulating the connection as to the etiology of mesothelioma resulted from an unforeseeable difference in the carcinogenicity of various asbestos and mineral fiber types and was compounded by the very long latency of the disease. Unfortunately, the use of a single term, asbestos, to describe at least five fibrous silicate minerals, each with unique physical, chemical, and biological properties and not infrequently and naturally admixed, severely hampered scientific investigation into the occupational health risks. The field became confused and filled with debate. At the heart of the fiber type controversy lies a fundamentally differing view of the importance of biopersistence of various asbestos fibers in carcinogenesis. This review will deal with the epidemiology of mesothelioma with particular attention to the studies that elucidate the impact of various asbestos fiber types on the etiology of the disease. Semin Oncol 29:18-25.
If you found any of these studies interesting, please read them in their entirety. We all owe a great deal of thanks to the people who are researching these important issues.
Asbestos Lawsuits - Just What A Person Needs To Acknowledge
Asbestos Lawsuits - Just What A Person Needs To Acknowledge Relating To Asbestos Lawsuits
In the beginning with the the twentieth hundred years, equally United states and also English doctors noticed the increase inside health problems in which corresponded with all the greater utilization of asbestos lawsuits. Within 1906, an Uk physician reported the very first circumstance associated with asbestos lawsuitsis. By the 20's, lots of people acknowledged that jobs for instance asbestos lawsuits exploration generated illness. This particular motivated the federal government in order to carry out research around the safety regarding asbestos lawsuits within the thirties.
asbestos lawsuits is really a particular mineral soluble fiber more commonly utilized in a variety of building materials. These people are visible in roof shingles, shingle sidings, ceilings, bare concrete items, ground tiles, and even in a few papers items. These people could also be used inside vehicles for instance inside brakes, transmitting, clutch, gaskets, and even in the actual clutch. asbestos lawsuits is great inside combating accident as well as is a good fire-retardant. However, coming in contact with asbestos lawsuits might enforce a significant danger. It can be breathed in in to the lungs wherever it may cause a few cells build-up. Within a few years after coming in contact with asbestos lawsuits, it may trigger significant illnesses related in your lung or perhaps breathing. In some cases, it could also be the cause of dying. That's why you should know about removing asbestos lawsuits as well as the asbestos lawsuits rules required.
Now that you've got an idea on which asbestos lawsuits and also what it may cause, you need to have in mind the frequent sources of exposure to asbestos lawsuits. At home or in various buildings like the workplace or perhaps college, asbestos lawsuits could be found in ruined or going down hill insulation, acoustical supplies, fire proofing, and also floor ceramic tiles. It can be in the threshold, shingle siding, or even floor coverings. In business locations, especially in schools, restrictions state that masters, administration, or perhaps supervision needs to have a great asbestos lawsuits examination every 3 years, based on the location where the constructing can be found. This allows with regard to basic safety of everybody. Remember which it is your responsibility to maintain the students, teachers, and also staff secure in your constructing. Today however, those who find themselves employed in industries which involve exploration, producing, or using asbestos lawsuits should know the risk. Your place of work is one of the leading causes of asbestos lawsuits publicity.
Chemically, asbestos lawsuits mineral deposits tend to be silicate ingredients. They will contain atoms of o2 and also silicon in their molecular structure. asbestos lawsuits are utilized inside constructing as well as construction market sectors in order to reinforce cement as well as plastics; with regard to insulation, sound absorption, fireproofing as well as roof covering.
Home renovation is probably the most popular weekend earlier instances these days, along with a great number of motivated to boost their own homes and a lot doing the particular projects on their own. Nevertheless, should you be considering to begin virtually any home Do-it-yourself projects, then you need to know just a little regarding asbestos lawsuits as well as a few of the asbestos lawsuits hazards, to keep your family risk-free.
Once you breathe in asbestos lawsuits materials, you can get lung cancer and also mesothelioma. In the event you or somebody you adore is rolling out mesothelioma because of asbestos lawsuits exposure, you need to check with an asbestos lawsuits attorney concerning your privileges. For more information, call a great asbestos lawsuits lawyer from Williams Kherkher today.
If you feel supplies within your home that are within good condition may contain unreleased asbestos lawsuits dietary fiber, the buyer Product Security Commission indicates simply leaving behind these types of materials alone. Try to avoid managing and also scrubbing against anything that could include asbestos lawsuits, and look into the region frequently to make sure there aren't any rips, cry, or even chips within anything you believe could have asbestos lawsuits inside it. When the area can be simply avoided, the CPSC indicates merely departing this on your own even if you will find little breaks and also holes.
You might be aware of the fact that during The second world war, asbestos lawsuits was handed a subject referred to as 'miracle mineral' by numerous. This is because, in those days they will needed an excellent padding and building up broker as well as asbestos lawsuits was the right answer during the time. Actually, thousands of building and building market sectors made one of the most of these components with the help of them plastics as well as cements to make the actual constructions and also components more powerful. asbestos lawsuits can be simply divided into posts, that will by no means transmit electrical current which was seen as an key gain above a number of other insulators. Additionally, asbestos lawsuits is extremely resistant against various types of chemical compounds and heat as well.
Businesses is actually the most used way to obtain asbestos lawsuits coverage given that asbestos lawsuits is employed within insulations. People who smoke and non-smokers confronted with asbestos lawsuits are likely to build up lung cancers compared to those who find themselves not necessarily.
With regard to doctors to diagnose the actual onset of the illness, a complete physical examination will be called for. Your physician might also acquire an example of your phlegm (throw). This is examined within microscopic lense to find out in the event that cancer tissues are present.
In the beginning with the the twentieth hundred years, equally United states and also English doctors noticed the increase inside health problems in which corresponded with all the greater utilization of asbestos lawsuits. Within 1906, an Uk physician reported the very first circumstance associated with asbestos lawsuitsis. By the 20's, lots of people acknowledged that jobs for instance asbestos lawsuits exploration generated illness. This particular motivated the federal government in order to carry out research around the safety regarding asbestos lawsuits within the thirties.
asbestos lawsuits is really a particular mineral soluble fiber more commonly utilized in a variety of building materials. These people are visible in roof shingles, shingle sidings, ceilings, bare concrete items, ground tiles, and even in a few papers items. These people could also be used inside vehicles for instance inside brakes, transmitting, clutch, gaskets, and even in the actual clutch. asbestos lawsuits is great inside combating accident as well as is a good fire-retardant. However, coming in contact with asbestos lawsuits might enforce a significant danger. It can be breathed in in to the lungs wherever it may cause a few cells build-up. Within a few years after coming in contact with asbestos lawsuits, it may trigger significant illnesses related in your lung or perhaps breathing. In some cases, it could also be the cause of dying. That's why you should know about removing asbestos lawsuits as well as the asbestos lawsuits rules required.
Now that you've got an idea on which asbestos lawsuits and also what it may cause, you need to have in mind the frequent sources of exposure to asbestos lawsuits. At home or in various buildings like the workplace or perhaps college, asbestos lawsuits could be found in ruined or going down hill insulation, acoustical supplies, fire proofing, and also floor ceramic tiles. It can be in the threshold, shingle siding, or even floor coverings. In business locations, especially in schools, restrictions state that masters, administration, or perhaps supervision needs to have a great asbestos lawsuits examination every 3 years, based on the location where the constructing can be found. This allows with regard to basic safety of everybody. Remember which it is your responsibility to maintain the students, teachers, and also staff secure in your constructing. Today however, those who find themselves employed in industries which involve exploration, producing, or using asbestos lawsuits should know the risk. Your place of work is one of the leading causes of asbestos lawsuits publicity.
Chemically, asbestos lawsuits mineral deposits tend to be silicate ingredients. They will contain atoms of o2 and also silicon in their molecular structure. asbestos lawsuits are utilized inside constructing as well as construction market sectors in order to reinforce cement as well as plastics; with regard to insulation, sound absorption, fireproofing as well as roof covering.
Home renovation is probably the most popular weekend earlier instances these days, along with a great number of motivated to boost their own homes and a lot doing the particular projects on their own. Nevertheless, should you be considering to begin virtually any home Do-it-yourself projects, then you need to know just a little regarding asbestos lawsuits as well as a few of the asbestos lawsuits hazards, to keep your family risk-free.
Once you breathe in asbestos lawsuits materials, you can get lung cancer and also mesothelioma. In the event you or somebody you adore is rolling out mesothelioma because of asbestos lawsuits exposure, you need to check with an asbestos lawsuits attorney concerning your privileges. For more information, call a great asbestos lawsuits lawyer from Williams Kherkher today.
If you feel supplies within your home that are within good condition may contain unreleased asbestos lawsuits dietary fiber, the buyer Product Security Commission indicates simply leaving behind these types of materials alone. Try to avoid managing and also scrubbing against anything that could include asbestos lawsuits, and look into the region frequently to make sure there aren't any rips, cry, or even chips within anything you believe could have asbestos lawsuits inside it. When the area can be simply avoided, the CPSC indicates merely departing this on your own even if you will find little breaks and also holes.
You might be aware of the fact that during The second world war, asbestos lawsuits was handed a subject referred to as 'miracle mineral' by numerous. This is because, in those days they will needed an excellent padding and building up broker as well as asbestos lawsuits was the right answer during the time. Actually, thousands of building and building market sectors made one of the most of these components with the help of them plastics as well as cements to make the actual constructions and also components more powerful. asbestos lawsuits can be simply divided into posts, that will by no means transmit electrical current which was seen as an key gain above a number of other insulators. Additionally, asbestos lawsuits is extremely resistant against various types of chemical compounds and heat as well.
Businesses is actually the most used way to obtain asbestos lawsuits coverage given that asbestos lawsuits is employed within insulations. People who smoke and non-smokers confronted with asbestos lawsuits are likely to build up lung cancers compared to those who find themselves not necessarily.
With regard to doctors to diagnose the actual onset of the illness, a complete physical examination will be called for. Your physician might also acquire an example of your phlegm (throw). This is examined within microscopic lense to find out in the event that cancer tissues are present.
Asbestos Exposure And The Increased Risk Of Carcinoma
Mesothelioma is a deadly disease that has taken thousands of lives. The more public awareness that is brought to this disease, the better. One interesting study is called, Unsuspected exposure to asbestos and bronchogenic carcinoma by K M Martischnig, D J Newell, W C Barnsley, W K Cowan, E L Feinmann, E Oliver - Br Med J 1977;1:746-749 (19 March). Here is an excerpt: Two hundred and fifty men admitted to a thoracic surgical centre and matched controls were questioned in detail about their occupations after leaving school and their smoking habits. Of 201 men with confirmed bronchial carcinoma 58 gave a history of occupational exposure to asbestos, whereas only 29 out of 201 men matched for age and residential area who were admitted with other diseases gave such a history. This difference was statistically highly significant. The usual association of bronchial carcinoma with heavy smoking was observed, but asbestos exposure increased the risk of carcinoma whatever the level of smoking. These results are consistent with the hypothesis that asbestos exposure and the level of smoking act independently in causing bronchial carcinoma. The patients with carcinoma who had been exposed to asbestos presented on average three years earlier than those who had not been exposed. Asbestos regulations have eliminated the risk of exposure to workers in scheduled industries, so asbestos-induced diseases will probably be increasingly found among the many workers who have had incidental exposure to asbestos. It is therefore important to take a full occupational history.
Another interesting study is called, Asbestos and mesothelioma: Worldwide trends by Laurie Kazan-Allen - Volume 49, Supplement 1, Pages S3-S8 (July 2005). Here is an excerpt: Summary - A correlation between national asbestos consumption and the incidence of asbestos disease, including mesothelioma, has been observed. Towards the end of the 20th century, governments in many developed countries banned or seriously restricted the use of asbestos. As a result, global asbestos producers have engaged in aggressive marketing campaigns to sell asbestos to developing countries; consumption of white asbestos is increasing in Asia, Latin America and the Commonwealth of Independent States. In most of the countries, there is little, if any, control on hazardous asbestos exposures from occupational, environmental and domestic sources. It is likely that the lethal asbestos harvest which is occurring in the U.S., the UK and Australia will be reproduced in the developing world.
A third study worth examining is called, Response of mouse lung to crocidolite asbestos, Minimal fibrotic reaction to short fibres by Dr Ian Y. R. Adamson, Drummond H. Bowden - Department of Pathology, University of Manitoba, Winnipeg, Canada - The Journal of Pathology Volume 152 Issue 2, Pages 99 107. Here is an excerpt: Abstract - To determine the relationship between the development of pulmonary fibrosis and the size of deposited asbestos, we prepared a pure sample of short crocidolite fibres and instilled 0.5 mg of 0.1 mg to the lungs of mice. Animals were killed up to 20 weeks later with 3H thymidine injected 1 h before death. By bronchoalveolar lavage, there was a rapid transient increase in polymorph neutrophils (PMN) and in glucosaminidase levels; alveolar macrophage (AM) numbers were elevated in the 0.5 mg group for eight weeks. Most fibres were phagocytized by AM, many of which were heavily laden and cleared from the lung over the 20 week period. Some fibres were seen in type 1 epithelial cells, frequently associated with cell injury. From cell kinetic studies, a very brief proliferative response was seen in bronchiolar epithelial and Type 2 alveolar epithelial cells. A greater response was seen in interstitial fibroblasts which showed increased labelling up to two weeks after 0.5 mg asbestos. However no granulomas were seen and very little fibrosis was found by morphology or by biochemistry at any time after 0.5 mg; no fibrosis was seen after instilling 0.1 mg. The results show that a high dose of exclusively short asbestos fibres produces minimal lung injury and fibrosis in spite of long standing macrophage-fibre interaction in the alveoli.
If you found any of these studies interesting, please read them in their entirety. We all owe a great deal of thanks to the people who are researching these important issues.
Another interesting study is called, Asbestos and mesothelioma: Worldwide trends by Laurie Kazan-Allen - Volume 49, Supplement 1, Pages S3-S8 (July 2005). Here is an excerpt: Summary - A correlation between national asbestos consumption and the incidence of asbestos disease, including mesothelioma, has been observed. Towards the end of the 20th century, governments in many developed countries banned or seriously restricted the use of asbestos. As a result, global asbestos producers have engaged in aggressive marketing campaigns to sell asbestos to developing countries; consumption of white asbestos is increasing in Asia, Latin America and the Commonwealth of Independent States. In most of the countries, there is little, if any, control on hazardous asbestos exposures from occupational, environmental and domestic sources. It is likely that the lethal asbestos harvest which is occurring in the U.S., the UK and Australia will be reproduced in the developing world.
A third study worth examining is called, Response of mouse lung to crocidolite asbestos, Minimal fibrotic reaction to short fibres by Dr Ian Y. R. Adamson, Drummond H. Bowden - Department of Pathology, University of Manitoba, Winnipeg, Canada - The Journal of Pathology Volume 152 Issue 2, Pages 99 107. Here is an excerpt: Abstract - To determine the relationship between the development of pulmonary fibrosis and the size of deposited asbestos, we prepared a pure sample of short crocidolite fibres and instilled 0.5 mg of 0.1 mg to the lungs of mice. Animals were killed up to 20 weeks later with 3H thymidine injected 1 h before death. By bronchoalveolar lavage, there was a rapid transient increase in polymorph neutrophils (PMN) and in glucosaminidase levels; alveolar macrophage (AM) numbers were elevated in the 0.5 mg group for eight weeks. Most fibres were phagocytized by AM, many of which were heavily laden and cleared from the lung over the 20 week period. Some fibres were seen in type 1 epithelial cells, frequently associated with cell injury. From cell kinetic studies, a very brief proliferative response was seen in bronchiolar epithelial and Type 2 alveolar epithelial cells. A greater response was seen in interstitial fibroblasts which showed increased labelling up to two weeks after 0.5 mg asbestos. However no granulomas were seen and very little fibrosis was found by morphology or by biochemistry at any time after 0.5 mg; no fibrosis was seen after instilling 0.1 mg. The results show that a high dose of exclusively short asbestos fibres produces minimal lung injury and fibrosis in spite of long standing macrophage-fibre interaction in the alveoli.
If you found any of these studies interesting, please read them in their entirety. We all owe a great deal of thanks to the people who are researching these important issues.
Sunday, August 26, 2012
Wr Grace Faces Criminal Fines In Asbestos Suit
Federal prosecutors have initiated a trial against a mining company in Libby, Montana in response to thousands of injuries and hundreds of deaths related to toxic asbestos exposure. Prosecutors began the trial in late February 2009 in a Missoula courthouse, alleging that the defendant corporation, W.R. Grace & Company released asbestos despite its knowledge of the dangers and potential health risks associated with the toxic mineral.
W.R. Grace Faces Asbestos-Related Criminal Charges
W.R. Grace operated a Libby, Montana vermiculite mine until 1990. The vermiculite, which has been used in various applications was contaminated with toxic asbestos. Prosecutors allege that W.R. Grace knew of the grave dangers associated with asbestos, but continued to operate the mine without warning employees or families living near the mine of the potential heath risks.
The company is now facing criminal charges in what has been named the most significant environmental criminal prosecution thats ever been brought, by David Uhlmann the Justice Departments former top prosecutor of environmental crimes.
Despite denial of conspiracy, the defendant corporation is facing criminal charges including:
* Conspiring to conceal and misrepresent the dangers of the asbestos-contaminated vermiculite that they were mining.
* Attempting to defraud the U.S. and others involved in the investigation against them in 1999 by impairing, impeding and frustrating the Environmental Protection Agency and other government agencies.
* Engaging in wire fraud and obstruction of justice.
W.R. Grace is facing up to $280 million in criminal fines and five of its executives are facing prison time in the asbestos suit.
Thousands of Families Affected by Asbestos Exposure
According to reports, more than 1,000 individuals have been injured and more than 200 have died as a result of the asbestos exposure in Libby. Asbestos, in its natural state, is not harmful; however, if the asbestos is broken down and disturbed (as it is in the mining process), its fiber separate and form a toxic dust that can be easily inhaled and ingested.
Once ingested, the asbestos embeds itself into the bodys vital organs and overtime, can lead to the development of fatal diseases including mesothelioma, lung cancer and asbestosis.
Witnesses Include Families of Individuals Killed from Asbestos Diseases
Among the first witnesses to take the stand in the trial are those whose loved ones died as a result of an asbestos disease. According to reports, the family members who presented their arguments stated they were never warned about the potential asbestos side effects of. One woman even stated that, as children, they used to play with the dust and even put it in their mouths.
Other Libby residents stated they wouldnt have raised their children so close to the mine had they known of the dangers they were subjected to.
More Asbestos Diseases Will Continue to Surface
Because asbestos-caused diseases can take up to 50 years to develop, Libby residents and W.R. Grace employees have been affected without even knowing it. Thousands more individuals will potentially feel the effects of the defendants actions in the years to come.
(Source: CNN)
For more information about asbestos exposure or the criminal allegations against W.R. Grace and Company, please contact the Mesothelioma Treatment Center today. We will connect you with an experienced asbestos attorney who is familiar with the dangers of asbestos.
W.R. Grace Faces Asbestos-Related Criminal Charges
W.R. Grace operated a Libby, Montana vermiculite mine until 1990. The vermiculite, which has been used in various applications was contaminated with toxic asbestos. Prosecutors allege that W.R. Grace knew of the grave dangers associated with asbestos, but continued to operate the mine without warning employees or families living near the mine of the potential heath risks.
The company is now facing criminal charges in what has been named the most significant environmental criminal prosecution thats ever been brought, by David Uhlmann the Justice Departments former top prosecutor of environmental crimes.
Despite denial of conspiracy, the defendant corporation is facing criminal charges including:
* Conspiring to conceal and misrepresent the dangers of the asbestos-contaminated vermiculite that they were mining.
* Attempting to defraud the U.S. and others involved in the investigation against them in 1999 by impairing, impeding and frustrating the Environmental Protection Agency and other government agencies.
* Engaging in wire fraud and obstruction of justice.
W.R. Grace is facing up to $280 million in criminal fines and five of its executives are facing prison time in the asbestos suit.
Thousands of Families Affected by Asbestos Exposure
According to reports, more than 1,000 individuals have been injured and more than 200 have died as a result of the asbestos exposure in Libby. Asbestos, in its natural state, is not harmful; however, if the asbestos is broken down and disturbed (as it is in the mining process), its fiber separate and form a toxic dust that can be easily inhaled and ingested.
Once ingested, the asbestos embeds itself into the bodys vital organs and overtime, can lead to the development of fatal diseases including mesothelioma, lung cancer and asbestosis.
Witnesses Include Families of Individuals Killed from Asbestos Diseases
Among the first witnesses to take the stand in the trial are those whose loved ones died as a result of an asbestos disease. According to reports, the family members who presented their arguments stated they were never warned about the potential asbestos side effects of. One woman even stated that, as children, they used to play with the dust and even put it in their mouths.
Other Libby residents stated they wouldnt have raised their children so close to the mine had they known of the dangers they were subjected to.
More Asbestos Diseases Will Continue to Surface
Because asbestos-caused diseases can take up to 50 years to develop, Libby residents and W.R. Grace employees have been affected without even knowing it. Thousands more individuals will potentially feel the effects of the defendants actions in the years to come.
(Source: CNN)
For more information about asbestos exposure or the criminal allegations against W.R. Grace and Company, please contact the Mesothelioma Treatment Center today. We will connect you with an experienced asbestos attorney who is familiar with the dangers of asbestos.
Pleural Thickening And Profusion Resulting From Asbestos Exposure
Asbestos exposure is a known cause of cancer. A plethora of research has been done in the past to establish causation. One interesting study is called, Asbestos exposure and asbestos-related pleural and parenchymal disease associations with immune imbalance by Sprince NL, Oliver LC, McLoud TC, Eisen EA, Christiani DC, Ginns LC - Am Rev Respir Dis. 1991 Apr;143(4 Pt 1):822-8. Medical Services Pulmonary and Critical Care Unit, Massachusetts General Hospital, Boston, Massachusetts. Here is an excerpt: Abstract - The study hypothesis was that asbestos exposure and asbestos-related pleural plaques and interstitial disease are associated with (1) immune imbalances favoring helper-inducer T-cell subsets in blood and bronchoalveolar lavage (BAL) and (2) T-lymphocyte accumulation in BAL. One hundred twenty-two asbestos-exposed subsets (AES), including 27 nonsmokers (NS), were evaluated and compared with 10 unexposed normal subjects. Data were collected on medical, smoking, and occupational histories, physical examination, spirometry, lung volumes, single-breath DLCO, chest films read by a "B" reader, and T-lymphocyte characterization in blood and BAL using flow cytometry analysis of monoclonal-antibody-treated cells. On average, AES were 47 yr of age and had 23 yr of asbestos exposure. Fifty-eight (48%) had pleural thickening, and seven (6%) had profusion greater than or equal to 1/0. In blood, asbestos-exposed NS had lower total and percent CD8 and lower total CD3 than did normal subjects. In BAL, asbestos-exposed NS had higher total CD3 than did normal subjects. Among AES, increased asbestos exposure was associated with increased percent CD8 in BAL and decreases in both percent lymphocytes and total CD8 in blood. Increase in CD4/CD8 ratio in BAL were associated with pleural thickening. In those seven with profusion greater than or equal to 1/0, there was increased percent CD4 in blood and decreased percent CD8 in BAL. These results suggest immune imbalance favoring helper-inducer T-cell subsets in association with asbestos exposure systemically and with pleural plaques in BAL.
A second study is called, Changing attitudes and opinions regarding asbestos and cancer 1934-1965 by Enterline PE. Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, PA 15261. Am J Ind Med. 1991;20(5):685-700. Here is an excerpt: Literature published in the years 1934-1965 was reviewed to determine attitudes and opinions of scientists as to whether asbestos is a cause of cancer. In Germany, the issue was decided in 1943 when the government decreed that lung cancer, when associated with asbestosis (of any degree), was an occupational disease. In the United States, however, there was no consensus on the issue until 1964. Opinions of scientists over a 22 year period are shown and the contributions of various cultural, social, economic and political factors to these opinions are discussed. A lack of experimental and epidemiological evidence played a major role in delaying a consensus. Other important factors included a rejection of science conducted outside of the U.S. during this period, particularly a rejection of German scientific thought during and after WWII, and a rejection of clinical evidence in favor of epidemiological investigations. Individual writers rarely changed their minds on the subject of asbestos as a cause of cancer.
If you found any of these studies interesting, please read them in their entirety. We all owe a great deal of thanks to the people who are researching these important issues.
A second study is called, Changing attitudes and opinions regarding asbestos and cancer 1934-1965 by Enterline PE. Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, PA 15261. Am J Ind Med. 1991;20(5):685-700. Here is an excerpt: Literature published in the years 1934-1965 was reviewed to determine attitudes and opinions of scientists as to whether asbestos is a cause of cancer. In Germany, the issue was decided in 1943 when the government decreed that lung cancer, when associated with asbestosis (of any degree), was an occupational disease. In the United States, however, there was no consensus on the issue until 1964. Opinions of scientists over a 22 year period are shown and the contributions of various cultural, social, economic and political factors to these opinions are discussed. A lack of experimental and epidemiological evidence played a major role in delaying a consensus. Other important factors included a rejection of science conducted outside of the U.S. during this period, particularly a rejection of German scientific thought during and after WWII, and a rejection of clinical evidence in favor of epidemiological investigations. Individual writers rarely changed their minds on the subject of asbestos as a cause of cancer.
If you found any of these studies interesting, please read them in their entirety. We all owe a great deal of thanks to the people who are researching these important issues.
Saturday, August 25, 2012
Mesothelioma Research And Bridging The Gap
Continued research regarding mesothelioma and the link to asbestos exposure is necessary if we ever hope to find a cure. Imagine someone you love returning home from the second world war. They find a job as an auto mechanic, raise a family, and play by the rules. Decades later, they tragically die from mesothelioma cancer because someone failed to warn them of the dangers of asbestos fibers. Does any reasonable person believe this is fair or just? Of course not. Unfortunately, we cannot go back in time and prevent the asbestos exposure. But what we can do is try to promote public awareness about this deadly disease and highlight some of the great research being done.
One interesting study is called, Malignant mesothelioma: attributable risk of asbestos exposure. By R Spirtas, E F Heineman, L Bernstein, G W Beebe, R J Keehn, A Stark, B L Harlow, and J Benichou - Occup Environ Med 1994;51:804-811 doi:10.1136/oem.51.12.804. Here is an excerpt:
OBJECTIVES--To evaluate a case-control study of malignant mesothelioma through patterns of exposure to asbestos based upon information from telephone interviews with next of kin. METHODS--Potential cases, identified from medical files and death certificates, included all people diagnosed with malignant mesothelioma and registered during 1975-1980 by the Los Angeles County Cancer Surveillance Program, the New York State Cancer Registry (excluding New York City), and 39 large Veterans Administration hospitals. Cases whose diagnosis was confirmed in a special pathology review as definite or probable mesothelioma (n = 208) were included in the analysis. Controls (n = 533) had died of other causes, excluding cancer, respiratory disease, suicide, or violence. Direct exposure to asbestos was determined from responses to three types of questions: specific queries as to any exposure to asbestos; occupational or non-vocational participation in any of nine specific activities thought to entail exposure to asbestos; and analysis of life-time work histories. Indirect exposures were assessed through residential histories and reported contact with family members exposed to asbestos. RESULTS--Among men with pleural mesothelioma the attributable risk (AR) for exposure to asbestos was 88% (95% confidence interval (95% CI) 76-95%). For men, the AR of peritoneal cancer was 58% (95% CI 20-89%). For women (both sites combined), the AR was 23% (95% CI 3-72%). The large differences in AR by sex are compatible with the explanations: a lower background incidence rate in women, lower exposure to asbestos, and greater misclassification among women. CONCLUSIONS--Most of the pleural and peritoneal mesotheliomas in the men studied were attributable to exposure to asbestos. The situation in women was less definitive.
Another good study is called, Chrysotile asbestos is the main cause of pleural mesothelioma by Allan H. Smith, MD, PhD, Catherine C. Wright, MPH
School of Public Health, University of California, Berkeley, CA. Here is an excerpt:
Abstract - In contrast to amphibole forms of asbestos, chrysotile asbestos is often claimed to be only a minor cause of malignant pleural mesothelioma, a highly fatal cancer of the lining of the thoracic cavity. In this article we examine the evidence from animal and human studies that relates to this issue. Reported data do not support widely quoted views regarding the relative inertness of chrysotile fibers in mesothelioma causation. In fact, examination of all pertinent studies makes it clear that chrysotile asbestos is similar in potency to amphibole asbestos. Since asbestos is the major cause of mesothelioma, and chrysotile constitutes 95% of all asbestos use world wide, it can be concluded that chrysotile asbestos is the main cause of pleural mesothelioma in humans."
If you found either of these excerpts interesting, I would urge you to read the studies in their entirety. We all owe a debt of gratitude to these researchers, and should do our best to promote public awareness. This article should not be construed as legal or medical advice.
One interesting study is called, Malignant mesothelioma: attributable risk of asbestos exposure. By R Spirtas, E F Heineman, L Bernstein, G W Beebe, R J Keehn, A Stark, B L Harlow, and J Benichou - Occup Environ Med 1994;51:804-811 doi:10.1136/oem.51.12.804. Here is an excerpt:
OBJECTIVES--To evaluate a case-control study of malignant mesothelioma through patterns of exposure to asbestos based upon information from telephone interviews with next of kin. METHODS--Potential cases, identified from medical files and death certificates, included all people diagnosed with malignant mesothelioma and registered during 1975-1980 by the Los Angeles County Cancer Surveillance Program, the New York State Cancer Registry (excluding New York City), and 39 large Veterans Administration hospitals. Cases whose diagnosis was confirmed in a special pathology review as definite or probable mesothelioma (n = 208) were included in the analysis. Controls (n = 533) had died of other causes, excluding cancer, respiratory disease, suicide, or violence. Direct exposure to asbestos was determined from responses to three types of questions: specific queries as to any exposure to asbestos; occupational or non-vocational participation in any of nine specific activities thought to entail exposure to asbestos; and analysis of life-time work histories. Indirect exposures were assessed through residential histories and reported contact with family members exposed to asbestos. RESULTS--Among men with pleural mesothelioma the attributable risk (AR) for exposure to asbestos was 88% (95% confidence interval (95% CI) 76-95%). For men, the AR of peritoneal cancer was 58% (95% CI 20-89%). For women (both sites combined), the AR was 23% (95% CI 3-72%). The large differences in AR by sex are compatible with the explanations: a lower background incidence rate in women, lower exposure to asbestos, and greater misclassification among women. CONCLUSIONS--Most of the pleural and peritoneal mesotheliomas in the men studied were attributable to exposure to asbestos. The situation in women was less definitive.
Another good study is called, Chrysotile asbestos is the main cause of pleural mesothelioma by Allan H. Smith, MD, PhD, Catherine C. Wright, MPH
School of Public Health, University of California, Berkeley, CA. Here is an excerpt:
Abstract - In contrast to amphibole forms of asbestos, chrysotile asbestos is often claimed to be only a minor cause of malignant pleural mesothelioma, a highly fatal cancer of the lining of the thoracic cavity. In this article we examine the evidence from animal and human studies that relates to this issue. Reported data do not support widely quoted views regarding the relative inertness of chrysotile fibers in mesothelioma causation. In fact, examination of all pertinent studies makes it clear that chrysotile asbestos is similar in potency to amphibole asbestos. Since asbestos is the major cause of mesothelioma, and chrysotile constitutes 95% of all asbestos use world wide, it can be concluded that chrysotile asbestos is the main cause of pleural mesothelioma in humans."
If you found either of these excerpts interesting, I would urge you to read the studies in their entirety. We all owe a debt of gratitude to these researchers, and should do our best to promote public awareness. This article should not be construed as legal or medical advice.
Mesothelioma Is Serious Cancer.
Mesothelioma is serious cancer and asbestos is main cause. During in 1940 and 1950s constructions community used asbestos as the best thing to happen after cement for construction industry. Asbestos was applied greatly in insulator and ceiling tiles in homes, schools and factories because to high degree of stability and resistance to very high temperatures.
Nonetheless, asbestos is capable of causing harm, contaminant. It has trend to break into small parts and remain stay in the air for longer durations. For individual who is that comes in contact it, becomes attackable to serious disease to lung cancer or mesothelioma lung cancers.
What types of Mesothelioma?
Name of Mesothelioma, asbestos related cancer, acquires its name from the mesothelium cells that are responsible for protecting and enabling easy movement of our vital organs such as lungs, heart and the abdomen in the body. Mesothelioma is generally of three types, pleural mesothelioma, peritoneal mesothelioma and pericardial mesothelioma.
If a person is suffering from hoarseness, difficulty in breathing, loss in weight, coughing, blood in sputum, chest pain, weak muscles, reduced tactile sensitivity, he may be suffering from Pleural mesothelioma or the cancer of lining of the lungs. This is the most common type of mesothelioma and almost two-thirds of the mesothelioma patients suffer from pleural mesothelioma. The Peritoneal mesothelioma or cancer of the lining of the abdomen causes impaired bowel motion, bloating, swelling in feet, and nausea. This is less common among mesothelioma patients and it affects one-third of the mesothelioma patients. Pericardial mesothelioma is of the cancer of lining of the heart. It is also caused because of asbestos exposure. However, its prevalence is rare. Pericardial mesothelioma manifests in the form of chest pain, palpitations and cough.
Lawsuits related to Mesothelioma:
The dangerous consequences of long term contact with asbestos and its linkage to mesothelioma cancers has led to several lawsuits against its manufacturers. The manufactures were claimed by the attorneys that they were aware of the capable of causing harm affects of asbestos exposure and yet persisted with its use for profit motives. This is the reason why juries have ordered stringent awards in many mesothelioma and asbestos related lawsuits.
Nonetheless, asbestos is capable of causing harm, contaminant. It has trend to break into small parts and remain stay in the air for longer durations. For individual who is that comes in contact it, becomes attackable to serious disease to lung cancer or mesothelioma lung cancers.
What types of Mesothelioma?
Name of Mesothelioma, asbestos related cancer, acquires its name from the mesothelium cells that are responsible for protecting and enabling easy movement of our vital organs such as lungs, heart and the abdomen in the body. Mesothelioma is generally of three types, pleural mesothelioma, peritoneal mesothelioma and pericardial mesothelioma.
If a person is suffering from hoarseness, difficulty in breathing, loss in weight, coughing, blood in sputum, chest pain, weak muscles, reduced tactile sensitivity, he may be suffering from Pleural mesothelioma or the cancer of lining of the lungs. This is the most common type of mesothelioma and almost two-thirds of the mesothelioma patients suffer from pleural mesothelioma. The Peritoneal mesothelioma or cancer of the lining of the abdomen causes impaired bowel motion, bloating, swelling in feet, and nausea. This is less common among mesothelioma patients and it affects one-third of the mesothelioma patients. Pericardial mesothelioma is of the cancer of lining of the heart. It is also caused because of asbestos exposure. However, its prevalence is rare. Pericardial mesothelioma manifests in the form of chest pain, palpitations and cough.
Lawsuits related to Mesothelioma:
The dangerous consequences of long term contact with asbestos and its linkage to mesothelioma cancers has led to several lawsuits against its manufacturers. The manufactures were claimed by the attorneys that they were aware of the capable of causing harm affects of asbestos exposure and yet persisted with its use for profit motives. This is the reason why juries have ordered stringent awards in many mesothelioma and asbestos related lawsuits.
Friday, August 24, 2012
Mesothelioma Hope And Help
The detrimental nature of being diagnosed with Mesothelioma has become widely recognized, and the unfortunate fact that asbestos-related illnesses are far reaching is only lately becoming understood. While most Mesothelioma patients have had jobs where they have had a higher than average contact with asbestos, it is now apparent that they brought home more than just hugs to their family members at the end of a long day.
Asbestos-related illnesses including Mesothelioma take many years to show their full effects, and often family members are now reporting cases of Mesothelioma simply from their exposure on the clothing their hard working loved one.
After over 50 years of unregulated asbestos usage throughout the United States, the number of Mesothelioma lawsuit cases skyrocketed. Attorneys were forced to become asbestos specialists, and Mesothelioma lawyers soon realized they were dealing with a long term epidemic.
In April 2003, it was suggested that the number of Mesothelioma cases had peaked, but Mesothelioma lawyers disagree as their rate for filing Mesothelioma lawsuits has once again begun a steady incline. Mesothelioma lawyers fear that their clients will not be able to bring enough companies into accountability as there is an overload of Mesothelioma lawsuits floating through district specific courtrooms.
New York Mesothelioma lawyers predict there will be a huge influx over the next ten years when the devastation of 911 is taken into account. The free floating asbestos that circulated through the city can have staggering effects on Mesothelioma lawsuits nationwide and perhaps even worldwide.
If you are in need of reaching a Mesothelioma settlement in order to take care of your medical needs as well as your familys financial future, Mesothelioma lawyers can assist you in understanding your rights to file a Mesothelioma lawsuit. Mesothelioma settlements are designed to protect your family in the event of your financial loss, as well as protect your family from the financial devastation that asbestos related cancers can cause on a familys income and ability to provide.
Mesothelioma lawyers predict that many people who were affected from the 911 destruction do not realize they have the right to sue the city. While numerous people, whether it was their job or not, risked their lives for the sake of others, the city has yet to come to a reasonable Mesothelioma settlement with those who were there to protect and serve, including those in governmental positions at the time. Do not hesitate to contact a Mesothelioma lawyer even if you simply suspect you are carrying an asbestos-related illness. Time is precious, and a Mesothelioma lawyer can help you make the most of your time.
Asbestos-related illnesses including Mesothelioma take many years to show their full effects, and often family members are now reporting cases of Mesothelioma simply from their exposure on the clothing their hard working loved one.
After over 50 years of unregulated asbestos usage throughout the United States, the number of Mesothelioma lawsuit cases skyrocketed. Attorneys were forced to become asbestos specialists, and Mesothelioma lawyers soon realized they were dealing with a long term epidemic.
In April 2003, it was suggested that the number of Mesothelioma cases had peaked, but Mesothelioma lawyers disagree as their rate for filing Mesothelioma lawsuits has once again begun a steady incline. Mesothelioma lawyers fear that their clients will not be able to bring enough companies into accountability as there is an overload of Mesothelioma lawsuits floating through district specific courtrooms.
New York Mesothelioma lawyers predict there will be a huge influx over the next ten years when the devastation of 911 is taken into account. The free floating asbestos that circulated through the city can have staggering effects on Mesothelioma lawsuits nationwide and perhaps even worldwide.
If you are in need of reaching a Mesothelioma settlement in order to take care of your medical needs as well as your familys financial future, Mesothelioma lawyers can assist you in understanding your rights to file a Mesothelioma lawsuit. Mesothelioma settlements are designed to protect your family in the event of your financial loss, as well as protect your family from the financial devastation that asbestos related cancers can cause on a familys income and ability to provide.
Mesothelioma lawyers predict that many people who were affected from the 911 destruction do not realize they have the right to sue the city. While numerous people, whether it was their job or not, risked their lives for the sake of others, the city has yet to come to a reasonable Mesothelioma settlement with those who were there to protect and serve, including those in governmental positions at the time. Do not hesitate to contact a Mesothelioma lawyer even if you simply suspect you are carrying an asbestos-related illness. Time is precious, and a Mesothelioma lawyer can help you make the most of your time.
Is It Possible To Get A Settlement If You Have
Is It Possible To Get A Settlement If You Have Been Exposed To Asbestos
Lung cancer and asbestosis, a chronic and progressive lung disorder, can be brought on by inhaling asbestos fibers. After it has been sucked into the lungs it may take as many as 15 to 60 years or more to present with disease symptoms. This extended latency period frequently makes it tricky to identify what caused it.
Being exposed to asbestos particles in the workplace can result in mesothelioma and other cancerous conditions. About 70 to 80 percent of all mesothelioma patients were exposed to asbestos fibers at their work. The exposure has customarily occurred decades previous and may possibly have been for a comparatively brief but heavy period.
During the 20th century asbestos was used commercially in many thousands of items. Millions of American citizens were put at risk unknowingly by being exposed to asbestos dust. Items containing asbestos were not at first believed to be dangerous, but in time many folks working for asbestos producers started developing cancer. Individuals laboring in asbestos mines, asbestos mills, heating or insulation companies, and various other occupations with asbestos have shown a considerable increase in the prevalence of the disease.
Today there are legal restrictions on the amount of asbestos exposure folks can receive at work because of the relationship between asbestos and numerous varieties of cancer. Employees exposed to asbestos fibers must now wear protective equipment that decreases their amount of exposure. Things like individual immune system strength may possibly play a major part in if a worker develops an asbestos-caused disorder. If you were diagnosed with asbestosis or some other asbestos-caused illness you may want to find asbestos law firms that focus in personal injury cases. Additionally, if you were exposed to asbestos fibers and have not yet developed any symptoms of cancer, you may still be able to receive compensation in a class action lawsuit.
For those who want to find the finest asbestos law firms it will demand a small amount of research. A few questions that you need the answers to are how many years they have been practicing, the number of asbestos suits they have handled, the number of mesothelioma suits they have handled, the total amount of their cases that were settled successfully, how many of their clients had to go to trial, whether or not there is a statute of limitations in the state you reside in for asbestos-associated claims, and the kind of documentation required from you to begin a lawsuit.
Determine what a typical financial settlement is for a case similar to yours. Also find out what the law firm will charge you for representation. The bulk of attorneys will manage cases like this by taking a percentage of the settlement money and won't even take the case if they think they won't be able to get a decent financial settlement for you.
When you have found the information you need concerning a few asbestos law firms and decided on one to hire the next duty is to pull together documents and information for the court case. Gathering as much information as possible provides you the best chance for a winning outcome. First and foremost you will need medical evidence that you have contracted cancer. You also have to identify where, when, and how long you were exposed to asbestos-containing items, the name of your employer, and if you know of any co-workers that contracted a similar sickness. Other workers or witnesses can usually help in confirming the location and time you were subjected to exposure.
The only recognized cause of mesothelioma is asbestos exposure, so your case may be simpler to demonstrate than you at first assumed. Most attorneys won't take a weaker case and will settle the bulk of cases they do handle out of court. An experienced lawyer will give an opinion to you on whether or not the settlement offer is fair or if it is best to take it to trial. After the lawyer gives you their opinion the ultimate determination of settling or going to trial rests in your hands.
There are several factors you should take note of prior to making your ultimate decision regarding the lawsuit. It may take a couple of years and perhaps more if you are determined to to go to trial. Can you handle a year or two of stress and tension without any guarantee that you will not go home empty handed? There are several questions that must be mulled over prior to coming up with a judgment that can affect your entire future.
Lung cancer and asbestosis, a chronic and progressive lung disorder, can be brought on by inhaling asbestos fibers. After it has been sucked into the lungs it may take as many as 15 to 60 years or more to present with disease symptoms. This extended latency period frequently makes it tricky to identify what caused it.
Being exposed to asbestos particles in the workplace can result in mesothelioma and other cancerous conditions. About 70 to 80 percent of all mesothelioma patients were exposed to asbestos fibers at their work. The exposure has customarily occurred decades previous and may possibly have been for a comparatively brief but heavy period.
During the 20th century asbestos was used commercially in many thousands of items. Millions of American citizens were put at risk unknowingly by being exposed to asbestos dust. Items containing asbestos were not at first believed to be dangerous, but in time many folks working for asbestos producers started developing cancer. Individuals laboring in asbestos mines, asbestos mills, heating or insulation companies, and various other occupations with asbestos have shown a considerable increase in the prevalence of the disease.
Today there are legal restrictions on the amount of asbestos exposure folks can receive at work because of the relationship between asbestos and numerous varieties of cancer. Employees exposed to asbestos fibers must now wear protective equipment that decreases their amount of exposure. Things like individual immune system strength may possibly play a major part in if a worker develops an asbestos-caused disorder. If you were diagnosed with asbestosis or some other asbestos-caused illness you may want to find asbestos law firms that focus in personal injury cases. Additionally, if you were exposed to asbestos fibers and have not yet developed any symptoms of cancer, you may still be able to receive compensation in a class action lawsuit.
For those who want to find the finest asbestos law firms it will demand a small amount of research. A few questions that you need the answers to are how many years they have been practicing, the number of asbestos suits they have handled, the number of mesothelioma suits they have handled, the total amount of their cases that were settled successfully, how many of their clients had to go to trial, whether or not there is a statute of limitations in the state you reside in for asbestos-associated claims, and the kind of documentation required from you to begin a lawsuit.
Determine what a typical financial settlement is for a case similar to yours. Also find out what the law firm will charge you for representation. The bulk of attorneys will manage cases like this by taking a percentage of the settlement money and won't even take the case if they think they won't be able to get a decent financial settlement for you.
When you have found the information you need concerning a few asbestos law firms and decided on one to hire the next duty is to pull together documents and information for the court case. Gathering as much information as possible provides you the best chance for a winning outcome. First and foremost you will need medical evidence that you have contracted cancer. You also have to identify where, when, and how long you were exposed to asbestos-containing items, the name of your employer, and if you know of any co-workers that contracted a similar sickness. Other workers or witnesses can usually help in confirming the location and time you were subjected to exposure.
The only recognized cause of mesothelioma is asbestos exposure, so your case may be simpler to demonstrate than you at first assumed. Most attorneys won't take a weaker case and will settle the bulk of cases they do handle out of court. An experienced lawyer will give an opinion to you on whether or not the settlement offer is fair or if it is best to take it to trial. After the lawyer gives you their opinion the ultimate determination of settling or going to trial rests in your hands.
There are several factors you should take note of prior to making your ultimate decision regarding the lawsuit. It may take a couple of years and perhaps more if you are determined to to go to trial. Can you handle a year or two of stress and tension without any guarantee that you will not go home empty handed? There are several questions that must be mulled over prior to coming up with a judgment that can affect your entire future.
How To Choose A Good Mesothelioma Lawyer
A good mesothelioma lawyer should have all the good qualities which include competence and knowledge. They should be able to give you a history of the disease as well as the strides that have been made in new cases that pertain to mesothelioma. Firstly, mesothelioma is a form of cancer that affects the protective lining of the abdomen, lungs and heart and it is caused by a natural occurring mineral called asbestos. Asbestos has been called the miracle mineral because it is one of the few substances resistant to fire. Therefore asbestos is a carcinogen or a substance that can cause cancer. The disease can manifest itself 30 to 50 years after exposure. If you are a patient of mesothelioma, you can file a case against the company you were working for. This is usually because the company needs to warn its workers of possible danger and failure to do this usually costs them when they are sued.
A good mesothelioma lawyer should have experience and should have won several cases. This is a case that will change your whole life, you therefore need to invest as much time as you can to make sure you have a good conclusion to the case. They should portray interest and dedication to the case and be ready to give it their best. Giving you brief history of what to expect goes a long way and, you will be more informed on the case from the beginning thanks to mesothelioma lawyer. Some middlemen have managed to disguise themselves as lawyers while all they want is a share of your reward when you win the case.
Therefore, knowing the qualifications of a lawyer can only help you determine whether they are suitable for your case. On the internet, there are so many options of mesothelioma lawyers and many are seeking just to benefit. Your main concern is that you win the case in the most professional manner possible. There are people who engage in a debate of judging the opportunistic 'professionals' and this may not be helpful in any case. One of the best thing that can shed so much light to your case is the experiences of other patients and their attorneys. Make it a priority to have this information so that you can avoid many pitfalls that they may have gotten into.
Choosing a good mesothelioma layer will take searching and dedication to seek the best. Find a layer from your locality to make the whole process convenient. Some lawyers on the internet advertise themselves paporting to be at a location they are not in. Make sure you see the lawyers office when you communicate with them. Know every aspect of the law beforehand in regard to mesothelioma. This will help save so much time and your lawyer can move forward and plan for the case. Finally, know how exactly you are going to settle the lawyers fee. Go for a contingency plan and this is where you pay them with you winnings in court. This is definitely convenient and many law firms have engaged in this and the major reason is to attract as many clients as possible. If you win the case, the lawyer gets a substantial amount of money.
A good mesothelioma lawyer should have experience and should have won several cases. This is a case that will change your whole life, you therefore need to invest as much time as you can to make sure you have a good conclusion to the case. They should portray interest and dedication to the case and be ready to give it their best. Giving you brief history of what to expect goes a long way and, you will be more informed on the case from the beginning thanks to mesothelioma lawyer. Some middlemen have managed to disguise themselves as lawyers while all they want is a share of your reward when you win the case.
Therefore, knowing the qualifications of a lawyer can only help you determine whether they are suitable for your case. On the internet, there are so many options of mesothelioma lawyers and many are seeking just to benefit. Your main concern is that you win the case in the most professional manner possible. There are people who engage in a debate of judging the opportunistic 'professionals' and this may not be helpful in any case. One of the best thing that can shed so much light to your case is the experiences of other patients and their attorneys. Make it a priority to have this information so that you can avoid many pitfalls that they may have gotten into.
Choosing a good mesothelioma layer will take searching and dedication to seek the best. Find a layer from your locality to make the whole process convenient. Some lawyers on the internet advertise themselves paporting to be at a location they are not in. Make sure you see the lawyers office when you communicate with them. Know every aspect of the law beforehand in regard to mesothelioma. This will help save so much time and your lawyer can move forward and plan for the case. Finally, know how exactly you are going to settle the lawyers fee. Go for a contingency plan and this is where you pay them with you winnings in court. This is definitely convenient and many law firms have engaged in this and the major reason is to attract as many clients as possible. If you win the case, the lawyer gets a substantial amount of money.
Thursday, August 23, 2012
Asbestos Settlement - The Most Significant Information In Regards To
Asbestos Settlement - The Most Significant Information In Regards To Asbestos Settlement
asbestos settlement are usually primarily referred to as the actual substance which in turn causes the actual dangerous disease Mesothelioma, an infrequent kind of cancer in which the internal organs of individuals grow to be surrounded by the cancerous covering of cells. asbestos settlement identifies any one of a small grouping of fibrous metamorphic nutrients with the hydrous the mineral magnesium silicate chemical substance loved ones.
One of the biggest styles within the last few 10 years continues to be the particular beginning of a big home renovation marketplace. Popular tv shows make remodeling homes and promoting for any profit appear really easy. The problem is that these displays fail to properly protect the potential risks and also safety measures in which need to take location whenever coping with more mature homes.
asbestos settlement is a part of the building market with regard to many years as well as through the entire 90's the item had been used in brand new structures. asbestos settlement is a poisonous fibrous materials found in building items like a fire retardant. These types of fibres happen to be proven to result in many dangerous or painful conditions with respect to the amount as well as form of a person experience. These include mesothelioma, lung cancer, and also asbestos settlementis.
Although physicians aren't in reality sure what exactly brings about this kind of disorder, some people might be genetically likely to be able in order to developing lung fibrosis without having any of the initiators listed above. However, probably the most existing research factors to microscopic pain within the lungs that causes nearly a great autoimmune-like overreaction of scar tissue accumulation. Thus, asbestos settlement fibres, that may split into microscopic items which are effortlessly inhaled as well as settle inside the bronchi, can cause pulmonary fibrosis and it is asbestos settlement-related subcategory, asbestos settlementis.
From contemporary nights the CT (digital tomography) check out is employed more frequently. CT is really a specific x-ray machine which shows chopped up photos regarding your body. CT check out regarding torso or perhaps abdomen shows the particular swellings within organs, some other primary, as well as lymph nodes. A contrast color can help towards the check out. CT reads display pleural effusion, pleural thickening, pleural calcification, distributing of cancer into upper body walls. However, CT usually do not really differentiate harmless asbestos settlement illness, lung cancer or mesothelioma. Doctors also employ CT scans regarding guiding hook aspiration associated with dubious pleural masses.
Mesothlioma cure is actually costly. Those who lost their particular much loved or perhaps those who find themselves experiencing this particular cancer, it's agonizing to cover the large quantity on treatments. It is usually good to adopt advice coming from Attorney. These Attorneys assist to find the remuneration from your business worries. The many charges with regard to medical center, surgical procedure, radiation treatment, funerals may be maintained using this.
MRI (permanent magnet resonance imaging) scan gives a sliced photo from the inside your body. It is best than X-ray or even CT check out because there is simply no rays of your body. Nevertheless it requires substantial moment. It sometimes uses up to twenty moments. As well as some individuals frightened to stay in the equipment for half an hour necessary for test. In addition to MRI has a constraint. The exam requires avoiding alloys inside your body (like steel important joints and other steel implants). MRI is actually not a regimen check, thus sometime it is not purchased. Permanent magnetic Resonance Image resolution is most often purchased to determine the level regarding tumor in order to strategy the actual surgery. MRI furthermore easier than CT tests shows enflamed lymph nodes and surface area regarding diaphragm as well as this will be significant for operative planning.
Contact with asbestos settlement will be hazardous to some person's health. Although the effects will never be apparent for many years, the creation of the condition is already going on inside the body as well as would certainly show itself following two decades or even more is long gone. asbestos settlement materials may settle on the textures for the particular essential organs from the entire body, including the lungs, center or the belly. This makes cells to endure alterations and down the road turn out to be cancers which eventually develop into cancer mesothelioma, which is incurable. These types of cancerous tissues can then metastasize to other internal organs of the entire body creating diverse signs regarding the illness.
The individual would generally seek seek advice from to be able to their medical doctor complaining associated with cough, upper body wall discomfort, a fever, exhaustion, problems associated with inhaling, as well as fat loss. Because these signs also indicate other illnesses like tuberculosis and other forms of lung cancer, it is important for the sufferer to give their medical doctor a whole background associated with their disease assuring when he had been exposed to asbestos settlement throughout the early decades. Following that, physical assessment as well as different laboratories could be used plus a biopsy would be performed. After which it he could diagnose this individual along with cancer mesothelioma and recommend proper treatment and/or palliative treatment.
Placing filling device directly into your own stomach and taking out the smooth inside of is named paracentesis Placing a needle directly into your chest and also draining the particular fluid is named thoracentesis.
asbestos settlement are usually primarily referred to as the actual substance which in turn causes the actual dangerous disease Mesothelioma, an infrequent kind of cancer in which the internal organs of individuals grow to be surrounded by the cancerous covering of cells. asbestos settlement identifies any one of a small grouping of fibrous metamorphic nutrients with the hydrous the mineral magnesium silicate chemical substance loved ones.
One of the biggest styles within the last few 10 years continues to be the particular beginning of a big home renovation marketplace. Popular tv shows make remodeling homes and promoting for any profit appear really easy. The problem is that these displays fail to properly protect the potential risks and also safety measures in which need to take location whenever coping with more mature homes.
asbestos settlement is a part of the building market with regard to many years as well as through the entire 90's the item had been used in brand new structures. asbestos settlement is a poisonous fibrous materials found in building items like a fire retardant. These types of fibres happen to be proven to result in many dangerous or painful conditions with respect to the amount as well as form of a person experience. These include mesothelioma, lung cancer, and also asbestos settlementis.
Although physicians aren't in reality sure what exactly brings about this kind of disorder, some people might be genetically likely to be able in order to developing lung fibrosis without having any of the initiators listed above. However, probably the most existing research factors to microscopic pain within the lungs that causes nearly a great autoimmune-like overreaction of scar tissue accumulation. Thus, asbestos settlement fibres, that may split into microscopic items which are effortlessly inhaled as well as settle inside the bronchi, can cause pulmonary fibrosis and it is asbestos settlement-related subcategory, asbestos settlementis.
From contemporary nights the CT (digital tomography) check out is employed more frequently. CT is really a specific x-ray machine which shows chopped up photos regarding your body. CT check out regarding torso or perhaps abdomen shows the particular swellings within organs, some other primary, as well as lymph nodes. A contrast color can help towards the check out. CT reads display pleural effusion, pleural thickening, pleural calcification, distributing of cancer into upper body walls. However, CT usually do not really differentiate harmless asbestos settlement illness, lung cancer or mesothelioma. Doctors also employ CT scans regarding guiding hook aspiration associated with dubious pleural masses.
Mesothlioma cure is actually costly. Those who lost their particular much loved or perhaps those who find themselves experiencing this particular cancer, it's agonizing to cover the large quantity on treatments. It is usually good to adopt advice coming from Attorney. These Attorneys assist to find the remuneration from your business worries. The many charges with regard to medical center, surgical procedure, radiation treatment, funerals may be maintained using this.
MRI (permanent magnet resonance imaging) scan gives a sliced photo from the inside your body. It is best than X-ray or even CT check out because there is simply no rays of your body. Nevertheless it requires substantial moment. It sometimes uses up to twenty moments. As well as some individuals frightened to stay in the equipment for half an hour necessary for test. In addition to MRI has a constraint. The exam requires avoiding alloys inside your body (like steel important joints and other steel implants). MRI is actually not a regimen check, thus sometime it is not purchased. Permanent magnetic Resonance Image resolution is most often purchased to determine the level regarding tumor in order to strategy the actual surgery. MRI furthermore easier than CT tests shows enflamed lymph nodes and surface area regarding diaphragm as well as this will be significant for operative planning.
Contact with asbestos settlement will be hazardous to some person's health. Although the effects will never be apparent for many years, the creation of the condition is already going on inside the body as well as would certainly show itself following two decades or even more is long gone. asbestos settlement materials may settle on the textures for the particular essential organs from the entire body, including the lungs, center or the belly. This makes cells to endure alterations and down the road turn out to be cancers which eventually develop into cancer mesothelioma, which is incurable. These types of cancerous tissues can then metastasize to other internal organs of the entire body creating diverse signs regarding the illness.
The individual would generally seek seek advice from to be able to their medical doctor complaining associated with cough, upper body wall discomfort, a fever, exhaustion, problems associated with inhaling, as well as fat loss. Because these signs also indicate other illnesses like tuberculosis and other forms of lung cancer, it is important for the sufferer to give their medical doctor a whole background associated with their disease assuring when he had been exposed to asbestos settlement throughout the early decades. Following that, physical assessment as well as different laboratories could be used plus a biopsy would be performed. After which it he could diagnose this individual along with cancer mesothelioma and recommend proper treatment and/or palliative treatment.
Placing filling device directly into your own stomach and taking out the smooth inside of is named paracentesis Placing a needle directly into your chest and also draining the particular fluid is named thoracentesis.
Shipyard Workers And Their Families Exposed To Hazardous Asbestos Dust
Shipyard Workers And Their Families Exposed To Hazardous Asbestos Dust And Mesothelioma
One group of people that have been particularly impacted by asbestos exposure is shipyward workers and their families. Asbestos was so prevalent in the construction of ships because of its fire retardant qualities and durability. During a ships construction, the workers would typically handle asbestos insulation products and consequently inhale large amounts of toxic dust. Unfortunately, many of these workers have died because of this asbestos exposure.
One thing we can all do is try to raise public awareness about asbestos exposure and the link to lung cancer and mesothelioma. One good study is called, Asbestos exposure: factors associated with excess cancer and respiratory disease mortality. By Henderson VL, and Enterline PE. Ann N Y Acad Sci. 1979; 330:117-26. Here is an excerpt:
A cohort of 1075 men who completed their working lifetimes with an asbestos company, worked at a facility in the United States, and retired with a company pension during the period 1941--67 was updated for deaths through 1973. The average length of employment was 25 years, and all had been exposed to asbestos dust. Respiratory cancer and pneumoconiosis-pulmonary fibrosis mortalities were examined in relation to cumulative dust exposure and to other factors after taking into account cumulative dust exposure. Men who worked in the production of asbestos cement pipe exhibited a higher risk of respiratory cancer, as did men with some crocidolite asbestos exposure. Because these two groups overlap, we could not be certain that crocidolite asbestos was responsible for the increased risk. Men working in general plant maintenance displayed a striking lack of deaths due to pneumoconiosis-pulmonary fibrosis, as compared with production workers and with maintenance personnel assigned to specific departments. Five mesothelioma deaths were observed at age 65 and over. Three of these deaths occurred during the period 1970--3.
Another good study worth looking at is called, Asbestos-related pleural disease and asbestosis: a comparison of CT and chest radiography by AC Friedman, SB Fiel, MS Fisher, PD Radecki, AS Lev-Toaff, and and DF Caroline - Department of Diagnostic Imaging, Temple University Hospital, Philadelphia, PA 19140. Here is an excerpt:
High-resolution CT (HRCT) has the ability to demonstrate both asbestos-related pleural disease and parenchymal abnormalities consistent with asbestosis. The role of CT in the diagnosis of asbestosis can be defined by comparing it with radiography. We evaluated 60 men who had a history of occupational exposure to asbestos and whose outside chest radiographs were considered abnormal. Chest radiographs (inside films) and HRCT were performed in all patients at our institution and were interpreted independently by experienced radiologists. Outside film results were compiled from the submitted reports. The final conclusion regarding the interpretation of the radiologic examinations was determined by consensus when disagreements existed. Positive predictive values (the likelihood that a positive report is correct) for pleural disease were: outside films 56%, inside films 79%, HRCT 100%. The positive predictive values for parenchymal disease were: outside films 51%, inside films 83%, HRCT 100%. The addition of HRCT to chest radiography is most useful in eliminating false-positive diagnoses of asbestos-related pleural disease caused by subpleural fat and false-positive diagnoses of parenchymal asbestosis in patients with extensive plaques or emphysema obscuring lung detail. The interpretation of chest radiographs in patients exposed to asbestos is often extremely difficult and subjective, and we recommend that positive findings (except calcified plaques) be confirmed with HRCT.
This article should not be construed as medical advice. Its purpose is to raise awareness. If you found either of these excerpts interesting, please read the studies in their entirety.
One group of people that have been particularly impacted by asbestos exposure is shipyward workers and their families. Asbestos was so prevalent in the construction of ships because of its fire retardant qualities and durability. During a ships construction, the workers would typically handle asbestos insulation products and consequently inhale large amounts of toxic dust. Unfortunately, many of these workers have died because of this asbestos exposure.
One thing we can all do is try to raise public awareness about asbestos exposure and the link to lung cancer and mesothelioma. One good study is called, Asbestos exposure: factors associated with excess cancer and respiratory disease mortality. By Henderson VL, and Enterline PE. Ann N Y Acad Sci. 1979; 330:117-26. Here is an excerpt:
A cohort of 1075 men who completed their working lifetimes with an asbestos company, worked at a facility in the United States, and retired with a company pension during the period 1941--67 was updated for deaths through 1973. The average length of employment was 25 years, and all had been exposed to asbestos dust. Respiratory cancer and pneumoconiosis-pulmonary fibrosis mortalities were examined in relation to cumulative dust exposure and to other factors after taking into account cumulative dust exposure. Men who worked in the production of asbestos cement pipe exhibited a higher risk of respiratory cancer, as did men with some crocidolite asbestos exposure. Because these two groups overlap, we could not be certain that crocidolite asbestos was responsible for the increased risk. Men working in general plant maintenance displayed a striking lack of deaths due to pneumoconiosis-pulmonary fibrosis, as compared with production workers and with maintenance personnel assigned to specific departments. Five mesothelioma deaths were observed at age 65 and over. Three of these deaths occurred during the period 1970--3.
Another good study worth looking at is called, Asbestos-related pleural disease and asbestosis: a comparison of CT and chest radiography by AC Friedman, SB Fiel, MS Fisher, PD Radecki, AS Lev-Toaff, and and DF Caroline - Department of Diagnostic Imaging, Temple University Hospital, Philadelphia, PA 19140. Here is an excerpt:
High-resolution CT (HRCT) has the ability to demonstrate both asbestos-related pleural disease and parenchymal abnormalities consistent with asbestosis. The role of CT in the diagnosis of asbestosis can be defined by comparing it with radiography. We evaluated 60 men who had a history of occupational exposure to asbestos and whose outside chest radiographs were considered abnormal. Chest radiographs (inside films) and HRCT were performed in all patients at our institution and were interpreted independently by experienced radiologists. Outside film results were compiled from the submitted reports. The final conclusion regarding the interpretation of the radiologic examinations was determined by consensus when disagreements existed. Positive predictive values (the likelihood that a positive report is correct) for pleural disease were: outside films 56%, inside films 79%, HRCT 100%. The positive predictive values for parenchymal disease were: outside films 51%, inside films 83%, HRCT 100%. The addition of HRCT to chest radiography is most useful in eliminating false-positive diagnoses of asbestos-related pleural disease caused by subpleural fat and false-positive diagnoses of parenchymal asbestosis in patients with extensive plaques or emphysema obscuring lung detail. The interpretation of chest radiographs in patients exposed to asbestos is often extremely difficult and subjective, and we recommend that positive findings (except calcified plaques) be confirmed with HRCT.
This article should not be construed as medical advice. Its purpose is to raise awareness. If you found either of these excerpts interesting, please read the studies in their entirety.
Wednesday, August 22, 2012
Mesothelioma Life Expectancy Beating The Silent Killer
It is to the turn of the twentieth century that the origins of this silent killer malignant mesothelioma can be traced. Many industrial giants at the time were introduced to the new material asbestos. Due to its high flexibility, this component was widely incorporated, as is still being used, to exploit its ingrained insulative properties. This very material claims the lives of many workers who were once working around it and using it. Relatives and friends of the person affected also remain at risk of contracting the disease.
Avoid exposure in the first place:
A person can get affected by asbestos indirectly. It is suggested that you avoid taking on any kind of roof repair or any other building repair work at home on your own. It is advisable to hire the services of a professional who understands the danger caused due to asbestos exposure. If mesothelioma is detected early, the chances of suppressing it are much higher. It is important to get yourself checked as early as possible to avoid further complications if you are ever in doubt about the risk of exposure.
It is prolonged exposure to asbestos that causes malignant mesothelioma; a deadly cancer. This malignant cancer is different from other forms of cancer due to the fat that it remains dormant within the carrier system for decades, anywhere between 30 and even 40 years! It is after this period that the symptoms become apparent. Mesothelioma cancer does not become malignant immediately but takes a number of years.
Hire an experienced mesothelioma attorney:
As compared to the yester years, today there is a higher diagnosis rate and chance of detection of this form of malignant mesothelioma. The disease raises its ugly head after 30 to 40 years and till then the carriers live with this deadly killer without experiencing any symptoms. Due to the negligence on the part of employers, thousands of cases have been brought before the courts around the world to help victims in improving mesothelioma life expectancy. Most of the cases are winning and victims are being paid in huge sums. This has given rise to a new breed of attorneys who specialize in this field.
Detect it early:
People affected by malignant mesothelioma cannot be cured with any amount of money at their disposal. But instead of turning the money down, it can be used to find various treatment options to relieve the pain and prolong life, thus improving mesothelioma life expectancy. The first thing is to work towards an early detection of this cancer, because only then can a more effective treatment be put in place to help in improving the survival rate. Mesothelioma has always been a silent killer and thousands have been exposed and affected by this killer disease already. Sit back, contemplate and identify asbestos exposure now to tap on potential help.
Avoid exposure in the first place:
A person can get affected by asbestos indirectly. It is suggested that you avoid taking on any kind of roof repair or any other building repair work at home on your own. It is advisable to hire the services of a professional who understands the danger caused due to asbestos exposure. If mesothelioma is detected early, the chances of suppressing it are much higher. It is important to get yourself checked as early as possible to avoid further complications if you are ever in doubt about the risk of exposure.
It is prolonged exposure to asbestos that causes malignant mesothelioma; a deadly cancer. This malignant cancer is different from other forms of cancer due to the fat that it remains dormant within the carrier system for decades, anywhere between 30 and even 40 years! It is after this period that the symptoms become apparent. Mesothelioma cancer does not become malignant immediately but takes a number of years.
Hire an experienced mesothelioma attorney:
As compared to the yester years, today there is a higher diagnosis rate and chance of detection of this form of malignant mesothelioma. The disease raises its ugly head after 30 to 40 years and till then the carriers live with this deadly killer without experiencing any symptoms. Due to the negligence on the part of employers, thousands of cases have been brought before the courts around the world to help victims in improving mesothelioma life expectancy. Most of the cases are winning and victims are being paid in huge sums. This has given rise to a new breed of attorneys who specialize in this field.
Detect it early:
People affected by malignant mesothelioma cannot be cured with any amount of money at their disposal. But instead of turning the money down, it can be used to find various treatment options to relieve the pain and prolong life, thus improving mesothelioma life expectancy. The first thing is to work towards an early detection of this cancer, because only then can a more effective treatment be put in place to help in improving the survival rate. Mesothelioma has always been a silent killer and thousands have been exposed and affected by this killer disease already. Sit back, contemplate and identify asbestos exposure now to tap on potential help.
Hazards Of Older Houses Asbestos And Lead
In the years following World War Two, the United States saw a housing boom followed shortly by a baby boom. The housing boom resulted in millions of new homes and neighborhoods across the country that were all brand new and equipped with the latest conveniences. Suburbs became a reality for many people and the 1950s were born.
Many of these homes are still standing and are still occupied by people. Unfortunately, some of these homes have not been renovated. Renovation, aside from cosmetic concerns, is a very important part of owning an older home. Not only does it increase the homes value but it removes the toxic hazards that are part and parcel of owning an older home.
In the 1940s and 1950s, the country had not quite realized the hazards and dangers of paint with lead in it. This means that a number of houses in the country built during this time were painted with lead paint. When a family re-painted, they frequently went right ahead and used more lead paint. As a consequence, an older home that has not been renovated can have many layers of lead paint sitting just under the surface of unleaded paint. This can pose a significant threat to the safety of any children living in the home.
Another hazard of older homes is asbestos. The 1940s and 1950s were, pretty much, boom decades for asbestos use. The fiber, because of its strength and insulation properties, was used in as many places as possible. While many of the locations of asbestos or items that contained asbestos might have been removed in the fifty to sixty years since the home was constructed, many others might not have been. Asbestos has been known to be used in everything from insulation to dry wall and even flooring tiles.
This potential threat makes renovation dangerous. An individual owning an older home who suspects that the home might contain asbestos in some piece of it should not attempt to demolish the walls on his or her own. While much more expensive, it is much safer to have a professional come in and at least test for asbestos, prior to tearing down the wall.
Homes that have been renovated may still have asbestos present in them. If the renovator was unaware of the threat of asbestos and knocked down the walls and tore out insulation haphazardly, the asbestos fibers in those items could have been released into the air. They could still be contaminating the home. As such, it is important to perform an asbestos check before moving in.
Older homes have loads of character and charm but they also have the possibility of having loads of hazards to go with them.
Many of these homes are still standing and are still occupied by people. Unfortunately, some of these homes have not been renovated. Renovation, aside from cosmetic concerns, is a very important part of owning an older home. Not only does it increase the homes value but it removes the toxic hazards that are part and parcel of owning an older home.
In the 1940s and 1950s, the country had not quite realized the hazards and dangers of paint with lead in it. This means that a number of houses in the country built during this time were painted with lead paint. When a family re-painted, they frequently went right ahead and used more lead paint. As a consequence, an older home that has not been renovated can have many layers of lead paint sitting just under the surface of unleaded paint. This can pose a significant threat to the safety of any children living in the home.
Another hazard of older homes is asbestos. The 1940s and 1950s were, pretty much, boom decades for asbestos use. The fiber, because of its strength and insulation properties, was used in as many places as possible. While many of the locations of asbestos or items that contained asbestos might have been removed in the fifty to sixty years since the home was constructed, many others might not have been. Asbestos has been known to be used in everything from insulation to dry wall and even flooring tiles.
This potential threat makes renovation dangerous. An individual owning an older home who suspects that the home might contain asbestos in some piece of it should not attempt to demolish the walls on his or her own. While much more expensive, it is much safer to have a professional come in and at least test for asbestos, prior to tearing down the wall.
Homes that have been renovated may still have asbestos present in them. If the renovator was unaware of the threat of asbestos and knocked down the walls and tore out insulation haphazardly, the asbestos fibers in those items could have been released into the air. They could still be contaminating the home. As such, it is important to perform an asbestos check before moving in.
Older homes have loads of character and charm but they also have the possibility of having loads of hazards to go with them.
Court Grows Weary Of Deceitful Claims
The difficulty lies in the question of what the legislature can and should do to attempt limiting asbestos and silica lawsuits, and this question has been raised in the state affairs committee hearing. The answer may be found in a member of the house, a medical doctor who authored the senate bill that has been pinpointed by certain business interests that note the influx of unfounded claims in the court system. These lobbyists are alleging that too many people get taken advantage of personal injury attorneys, who tend to be greedy and self-promoting. They can't do this, of course, without the help of doctors, who falsify or exaggerate X rays. Businesses are out thousands as they work to defend themselves against claims that have absolutely no merit.
Plaintiff's attorneys counter with the assertion that legislation is unnecessary, due to alterations in the law which direct asbestos litigation to a central judicial clearinghouse. However, some trial attorneys have been able to find a forum for a new class of cases which focus on injury claims related to silica.
By simply requiring the claimant to show actual physical effects of the damage, not just an x ray, it should be easy to distinguish between the real and fake cases, according to business interests. The bill being proposed would alter the bar association's current proposal requiring the claimants to satisfy a specific medical assessment involving a course of X-rays, doctor exams and breathing tests prior to being permitted to proceed with the proposed lawsuit.
The legislation would incorporate a pair of safeguards for those who can claim asbestos exposure, but have yet to suffer physical manifestations. First, it removes the past limitations of two year. Anyone who could not meet the medical standard of proof at a particular point in time, but could do so at a later date would have the ability to begin a lawsuit at any point in the future. Next, the bill would keep insurance companies from denying people their coverage, regardless of whether or not their medical tests show that they have been exposed to asbestos.
Many of these important safeguards are there to protect people, but some believe these medical standards are simply too strict. This new proposal would mean keeping the medical standards at their current level, and allowing workers to sue, but also allowing for a judge to refer the claim elsewhere to discuss its validity ahead of time. Under this proposal, workers would still have the same rights as before but the court would be able to separate out those claims that are baseless or fraudulent.
Raising medical standards won't solve the problem if doctors are lying, according to the house member. The bottom line is doctors won't be stopped from lying to a higher standard because of this bill. The state must find a way to reduce claims that do nothing more than waste the court's time so that justice can be meted out more quickly to those who truly need the court's aid. Workers who have a legitimate claim have the right to their day in court as soon as they can. The house member's amendment applies to the house bill, but he believes his idea is deserving of senate consideration as well.
Plaintiff's attorneys counter with the assertion that legislation is unnecessary, due to alterations in the law which direct asbestos litigation to a central judicial clearinghouse. However, some trial attorneys have been able to find a forum for a new class of cases which focus on injury claims related to silica.
By simply requiring the claimant to show actual physical effects of the damage, not just an x ray, it should be easy to distinguish between the real and fake cases, according to business interests. The bill being proposed would alter the bar association's current proposal requiring the claimants to satisfy a specific medical assessment involving a course of X-rays, doctor exams and breathing tests prior to being permitted to proceed with the proposed lawsuit.
The legislation would incorporate a pair of safeguards for those who can claim asbestos exposure, but have yet to suffer physical manifestations. First, it removes the past limitations of two year. Anyone who could not meet the medical standard of proof at a particular point in time, but could do so at a later date would have the ability to begin a lawsuit at any point in the future. Next, the bill would keep insurance companies from denying people their coverage, regardless of whether or not their medical tests show that they have been exposed to asbestos.
Many of these important safeguards are there to protect people, but some believe these medical standards are simply too strict. This new proposal would mean keeping the medical standards at their current level, and allowing workers to sue, but also allowing for a judge to refer the claim elsewhere to discuss its validity ahead of time. Under this proposal, workers would still have the same rights as before but the court would be able to separate out those claims that are baseless or fraudulent.
Raising medical standards won't solve the problem if doctors are lying, according to the house member. The bottom line is doctors won't be stopped from lying to a higher standard because of this bill. The state must find a way to reduce claims that do nothing more than waste the court's time so that justice can be meted out more quickly to those who truly need the court's aid. Workers who have a legitimate claim have the right to their day in court as soon as they can. The house member's amendment applies to the house bill, but he believes his idea is deserving of senate consideration as well.
Tuesday, August 21, 2012
Lung Cancer And Asbestos Exposure Determining The Cause
you were a pipefitter, steam fitter, auto mechanic, boiler maker, were in the construction industry, or demolition trade, the chances are pretty good that you were exposed to asbestos.Asbestos exposure has been linked to a deadly form of cancer known as mesothelioma.There has been a great deal of scholarly work done on this area, and we should all continue to try to increase public awareness of this deadly disease.One interesting study is called, Apoptosis is observed in mesothelial cells after exposure to crocidolite asbestos. By BruB KA, Quinlan TR, Fung H, Magae J, Vacek P, Taatjes DJ, and Mossman BT. - Department of Pathology, University of Vermont, Burlington 05405, USA. Am J Respir Cell Mol Biol. 1996 Jul;15(1):141-7.
Here is an excerpt: Asbestos causes protracted, dose-dependent increases in steady-state mRNA levels of the proto-oncogenes c-fos and c-jun, and AP-1 DNA-binding activity in normal rat pleural mesothelial (RPM) cells (1). To determine the phenotypic end points of overexpression of these early response genes by asbestos, both cell proliferation and apoptosis were examined in confluent RPM cells exposed to a range of concentrations (1.25 to 10 micrograms/cm2 dish) of crocidolite asbestos for 24 and 48 h. Quantitation of RPM cells pulsed with 5-bromo-2'-deoxyuridine revealed that asbestos caused dose-dependent decreases in cells undergoing DNA synthesis. Decreases in cell proliferation were accompanied by dose-related increases in apoptosis using (1) terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling (i.e., ApopTag technique), (2) 4',6-diamidino-2-phenylindole cell staining, and (3) fluorescent-activated cell sorter after incorporation of propidium iodide. Less striking but significant dose-related increases in apoptosis were observed in RPM cells exposed to H2O2 (300 microM), and no apoptosis was seen after exposure of cells to high concentrations (10 micrograms/cm2 dish) of glass beads. Our results are unique in that they demonstrate that asbestos induces apoptosis in mesothelial cells at concentrations eliciting increased expression of the proto-oncogenes c-fos and c-jun.
Another interesting study is called, Is lung cancer associated with asbestos exposure when there are no small opacities on the chest radiograph? by Wilkinson P, Hansell DM, Janssens J, Rubens M, Rudd RM, Taylor AN, McDonald C. - London Chest Hospital, UK. Lancet. 1995 Apr 29;345(8957):1074-8.Here is an excerpt:This study was designed to test the hypothesis that the risk of lung cancer from asbestos exposure is confined to persons with radiographic evidence of pulmonary fibrosis. Occupational and smoking histories were obtained from 271 patients with a confirmed diagnosis of primary lung cancer and 678 referents (279 with other respiratory disease and 399 with cardiac disease). Histories were reviewed blind to assess the timing, duration, and probability of exposure to asbestos. To allow for a lag between asbestos exposure and the development of lung cancer, subjects were classified by the time they had spent in an occupation entailing definite or probable exposure more than 15 years before diagnosis. The presence and extent of fibrosis was assessed blindly from chest radiographs by three readers and scored for small opacities with the ILO 1989 International Classification of Radiographs of the Pneumoconioses. 93 (34.3%) cases had worked in an occupation with definite or probable asbestos exposure compared with 176 (25.8%) referents (crude odds ratio for lung cancer 1.49, 95% CI 1.09-2.04). After adjustment for age, sex, smoking history, and area of referral, the odds ratio (95% CI) was 2.03 (1.00-4.13) in the subgroup of 211 with a median ILO score for small parenchymal opacities of 1/0 or more, and 1.56 (1.02-2.39) in the 738 with a score of 0/1 or less (ie, those without radiological evidence of pulmonary fibrosis). These results suggest that asbestos is associated with lung cancer even in the absence of radiologically apparent pulmonary fibrosis.
If you found either of these studies interesting or helpful, please read the entire studies.
Here is an excerpt: Asbestos causes protracted, dose-dependent increases in steady-state mRNA levels of the proto-oncogenes c-fos and c-jun, and AP-1 DNA-binding activity in normal rat pleural mesothelial (RPM) cells (1). To determine the phenotypic end points of overexpression of these early response genes by asbestos, both cell proliferation and apoptosis were examined in confluent RPM cells exposed to a range of concentrations (1.25 to 10 micrograms/cm2 dish) of crocidolite asbestos for 24 and 48 h. Quantitation of RPM cells pulsed with 5-bromo-2'-deoxyuridine revealed that asbestos caused dose-dependent decreases in cells undergoing DNA synthesis. Decreases in cell proliferation were accompanied by dose-related increases in apoptosis using (1) terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling (i.e., ApopTag technique), (2) 4',6-diamidino-2-phenylindole cell staining, and (3) fluorescent-activated cell sorter after incorporation of propidium iodide. Less striking but significant dose-related increases in apoptosis were observed in RPM cells exposed to H2O2 (300 microM), and no apoptosis was seen after exposure of cells to high concentrations (10 micrograms/cm2 dish) of glass beads. Our results are unique in that they demonstrate that asbestos induces apoptosis in mesothelial cells at concentrations eliciting increased expression of the proto-oncogenes c-fos and c-jun.
Another interesting study is called, Is lung cancer associated with asbestos exposure when there are no small opacities on the chest radiograph? by Wilkinson P, Hansell DM, Janssens J, Rubens M, Rudd RM, Taylor AN, McDonald C. - London Chest Hospital, UK. Lancet. 1995 Apr 29;345(8957):1074-8.Here is an excerpt:This study was designed to test the hypothesis that the risk of lung cancer from asbestos exposure is confined to persons with radiographic evidence of pulmonary fibrosis. Occupational and smoking histories were obtained from 271 patients with a confirmed diagnosis of primary lung cancer and 678 referents (279 with other respiratory disease and 399 with cardiac disease). Histories were reviewed blind to assess the timing, duration, and probability of exposure to asbestos. To allow for a lag between asbestos exposure and the development of lung cancer, subjects were classified by the time they had spent in an occupation entailing definite or probable exposure more than 15 years before diagnosis. The presence and extent of fibrosis was assessed blindly from chest radiographs by three readers and scored for small opacities with the ILO 1989 International Classification of Radiographs of the Pneumoconioses. 93 (34.3%) cases had worked in an occupation with definite or probable asbestos exposure compared with 176 (25.8%) referents (crude odds ratio for lung cancer 1.49, 95% CI 1.09-2.04). After adjustment for age, sex, smoking history, and area of referral, the odds ratio (95% CI) was 2.03 (1.00-4.13) in the subgroup of 211 with a median ILO score for small parenchymal opacities of 1/0 or more, and 1.56 (1.02-2.39) in the 738 with a score of 0/1 or less (ie, those without radiological evidence of pulmonary fibrosis). These results suggest that asbestos is associated with lung cancer even in the absence of radiologically apparent pulmonary fibrosis.
If you found either of these studies interesting or helpful, please read the entire studies.
Examination Of Asbestos Related Deaths And Controversial Issues
Keeping up with advances in mesothelioma research can be a difficult task. It seems like every day there is a new clinical trial being conducted or some new area being researched, and for good reason. Over 250,000 people have died as a result of asbestos exposure, and that number continues to climb. With continued effort and support, we can defeat this deadly disease.
One interesting study that looked into the relationship between asbestos related deaths and insulation workers is called, Asbestos-associated deaths among insulation workers in the United States and Canada, 1967-1987 by Selikoff, IJ Seidman, H Annals of the New York Academy of Sciences [ANN. N.Y. ACAD. SCI.]. Vol. 643, pp. 1-13. 1991. Here is an excerpt: In addition to showing an increase in deaths from asbestosis, a study of the causes of death in the 17,800 asbestos insulation workers followed prospectively for 20 years (1967-1986) has also showed significant increases in cancer in a variety of organs. These include lung cancer, pleural and peritoneal mesothelioma, gastrointestinal and other forms of cancer such as that of the oropharynx and buccal cavity, larynx, kidney, pancreas, gallbladder, and bile ducts. On the other hand, no increase were found for cancer of the urinary bladder, prostate, testis, primary cancer of the liver, and primary cancer of the brain, nor for melanoma, leukemia, or lymphoma. Since the study provided extensive data, reflecting 301,592.6 person-years of experience, one can be fairly confident that, at least for this asbestos exposure, at this time, the "negative" finding can be accepted with some assurance. Apparently each organ and tissue has its own neoplastic response to asbestos; in some tissues cancer risk is increased, but not in others.
Another study worth looking at is called, Asbestos-related disease in the workplace and the environment: controversial issues. By Churg A. - Department of Laboratory Medicine, University Hospital, University of British Columbia, Vancouver, Canada. Monogr Pathol. 1993;(36):54-77. Here is an excerpt: The classical pathologic diagnostic criteria for asbestosis, namely the presence of diffuse interstitial fibrosis resembling usual interstitial pneumonia, and asbestos bodies visible in ordinary tissue sections, have proved to withstand the test of time. Cases without asbestos bodies visible in routine or iron-stained tissue sections almost never turn out to be asbestosis. It should be remembered that workers with asbestos exposure develop all of the interstitial lung diseases to which the remainder of the populace is subject; some of these conditions are treatable and should not be misdiagnosed as asbestosis, which is not treatable. There is strong epidemiologic and pathologic evidence that the only association of asbestos exposure and lung cancer is the association of asbestosis and lung cancer. Thus, a lung cancer should only be attributed to asbestos exposure when asbestosis is present on clinical or pathologic grounds. The histologic type and location of the tumor are irrelevant in this regard. Analytical electron microscopy indicates that chrysotile asbestos does induce mesothelioma in man, but that extremely high levels of retained fibers, levels as high as those seen in cases of asbestosis, are required for this event to occur. The weight of the evidence suggests that exposure of the general population to the very low levels of chrysotile that are found in some public building (levels not greatly different from ambient air) will never produce mesothelioma, asbestosis, or lung cancer because these diseases all appear to require quite high-level occupational chrysotile exposure. Even if one accepts the ideas (probably wrong) that any level of asbestos exposure carries a risk of cancer, and that mathematical extrapolation of risk from high-level occupational exposure to low-level building exposure is scientifically valid, the calculated risks are much smaller than real everyday risks such as driving to work. Thus, exposure to asbestos at environmental levels appears to produce no real dangers to health.
For more information, please read these studies in their entirety and consider doing some independent research on your own.
One interesting study that looked into the relationship between asbestos related deaths and insulation workers is called, Asbestos-associated deaths among insulation workers in the United States and Canada, 1967-1987 by Selikoff, IJ Seidman, H Annals of the New York Academy of Sciences [ANN. N.Y. ACAD. SCI.]. Vol. 643, pp. 1-13. 1991. Here is an excerpt: In addition to showing an increase in deaths from asbestosis, a study of the causes of death in the 17,800 asbestos insulation workers followed prospectively for 20 years (1967-1986) has also showed significant increases in cancer in a variety of organs. These include lung cancer, pleural and peritoneal mesothelioma, gastrointestinal and other forms of cancer such as that of the oropharynx and buccal cavity, larynx, kidney, pancreas, gallbladder, and bile ducts. On the other hand, no increase were found for cancer of the urinary bladder, prostate, testis, primary cancer of the liver, and primary cancer of the brain, nor for melanoma, leukemia, or lymphoma. Since the study provided extensive data, reflecting 301,592.6 person-years of experience, one can be fairly confident that, at least for this asbestos exposure, at this time, the "negative" finding can be accepted with some assurance. Apparently each organ and tissue has its own neoplastic response to asbestos; in some tissues cancer risk is increased, but not in others.
Another study worth looking at is called, Asbestos-related disease in the workplace and the environment: controversial issues. By Churg A. - Department of Laboratory Medicine, University Hospital, University of British Columbia, Vancouver, Canada. Monogr Pathol. 1993;(36):54-77. Here is an excerpt: The classical pathologic diagnostic criteria for asbestosis, namely the presence of diffuse interstitial fibrosis resembling usual interstitial pneumonia, and asbestos bodies visible in ordinary tissue sections, have proved to withstand the test of time. Cases without asbestos bodies visible in routine or iron-stained tissue sections almost never turn out to be asbestosis. It should be remembered that workers with asbestos exposure develop all of the interstitial lung diseases to which the remainder of the populace is subject; some of these conditions are treatable and should not be misdiagnosed as asbestosis, which is not treatable. There is strong epidemiologic and pathologic evidence that the only association of asbestos exposure and lung cancer is the association of asbestosis and lung cancer. Thus, a lung cancer should only be attributed to asbestos exposure when asbestosis is present on clinical or pathologic grounds. The histologic type and location of the tumor are irrelevant in this regard. Analytical electron microscopy indicates that chrysotile asbestos does induce mesothelioma in man, but that extremely high levels of retained fibers, levels as high as those seen in cases of asbestosis, are required for this event to occur. The weight of the evidence suggests that exposure of the general population to the very low levels of chrysotile that are found in some public building (levels not greatly different from ambient air) will never produce mesothelioma, asbestosis, or lung cancer because these diseases all appear to require quite high-level occupational chrysotile exposure. Even if one accepts the ideas (probably wrong) that any level of asbestos exposure carries a risk of cancer, and that mathematical extrapolation of risk from high-level occupational exposure to low-level building exposure is scientifically valid, the calculated risks are much smaller than real everyday risks such as driving to work. Thus, exposure to asbestos at environmental levels appears to produce no real dangers to health.
For more information, please read these studies in their entirety and consider doing some independent research on your own.
Monday, August 20, 2012
Accident Lawyer Long Island Handles Legal Matter Involved In Car
Accident Lawyer Long Island Handles Legal Matter Involved In Car Accidents
Accidents can be very common in this modern day. Accident lawyers Long Island bound can find plenty of work. There are many instances accident lawyers Long Island mindful can get lots of work. For one thing, work places often harbor unsafe work environments. Car accidents are also very common in most places and this is especially true in Long Island. Another reason for needing accident lawyers in Long Island is for when you are injured randomly by no fault of your own.
Many places harbor unsafe work environments, and Long Island is not exempt. There can be hazardous chemicals in many work environments. There are many government regulations around the storage and use of these chemicals. Also, there can be lots of rules around how to deal with spills. When employers don't follow the regulations or make it difficult for the regulations to be followed, accidents can occur. Accident lawyer Long Island bound can help in these cases. There can be even more neglectful cases of work place injuries though. Some employers are very aware of work place dangers like asbestos insulation, faulty wiring or lack of carbon monoxide detectors. In these cases, accident lawyers Long Island conscious are essential. Oftentimes employers are reluctant to give employees time off or give disability. Accident lawyers can help employees fight for their rights and get what they need.
Car accidents in Long Island can be another fruitful source of litigation. Accident lawyers Long Island specialized are very familiar with these types of accidents. Car accidents are perhaps the most frequent type of accidents people fall prey to. Insurance companies are supposed to cover most accidents. Sometimes they try to take a long time to pay claims. Accident lawyers Long Island specialized know how to deal with insurance companies and get the money that people need. Other times, accident lawyer Long Island specialized, need to help with legal matter involved in car accidents. People unfortunately have run-ins with the law and need legal representation. Drunk driving is a very common problem and there is a strong demand for legal representation in their cases.
Anyone can suffer form a random injury at any time. Often these accidents are because someone was being neglectful of something. In Long Island, there are many places like this. Accidents can happen in both residential and commercial areas. Sometimes, people dont keep walkways clear. This can lead to serious accidents by innocent people. These accidents can have long term affects on people. They may not be able to work and still have many bills to pay. Accident lawyers Long Island conscious would want to help in these cases. Other times, a place could be in violation of certain health codes. People can get seriously sick from things like that. Accident lawyers Long Island conscious know what to do in such situations.
Accidents can be very common in this modern day. Accident lawyers Long Island bound can find plenty of work. There are many instances accident lawyers Long Island mindful can get lots of work. For one thing, work places often harbor unsafe work environments. Car accidents are also very common in most places and this is especially true in Long Island. Another reason for needing accident lawyers in Long Island is for when you are injured randomly by no fault of your own.
Many places harbor unsafe work environments, and Long Island is not exempt. There can be hazardous chemicals in many work environments. There are many government regulations around the storage and use of these chemicals. Also, there can be lots of rules around how to deal with spills. When employers don't follow the regulations or make it difficult for the regulations to be followed, accidents can occur. Accident lawyer Long Island bound can help in these cases. There can be even more neglectful cases of work place injuries though. Some employers are very aware of work place dangers like asbestos insulation, faulty wiring or lack of carbon monoxide detectors. In these cases, accident lawyers Long Island conscious are essential. Oftentimes employers are reluctant to give employees time off or give disability. Accident lawyers can help employees fight for their rights and get what they need.
Car accidents in Long Island can be another fruitful source of litigation. Accident lawyers Long Island specialized are very familiar with these types of accidents. Car accidents are perhaps the most frequent type of accidents people fall prey to. Insurance companies are supposed to cover most accidents. Sometimes they try to take a long time to pay claims. Accident lawyers Long Island specialized know how to deal with insurance companies and get the money that people need. Other times, accident lawyer Long Island specialized, need to help with legal matter involved in car accidents. People unfortunately have run-ins with the law and need legal representation. Drunk driving is a very common problem and there is a strong demand for legal representation in their cases.
Anyone can suffer form a random injury at any time. Often these accidents are because someone was being neglectful of something. In Long Island, there are many places like this. Accidents can happen in both residential and commercial areas. Sometimes, people dont keep walkways clear. This can lead to serious accidents by innocent people. These accidents can have long term affects on people. They may not be able to work and still have many bills to pay. Accident lawyers Long Island conscious would want to help in these cases. Other times, a place could be in violation of certain health codes. People can get seriously sick from things like that. Accident lawyers Long Island conscious know what to do in such situations.
Common Causes Of Tractor Accidents - What To Look Out
Common Causes Of Tractor Accidents - What To Look Out For
Heavy farm and construction equipment is, by nature, dangerous and potentially deadly. This is why such equipment is supposed to be manufactured according to the highest possible safety standards and operated only by trained professionals. However, even when tractors are operated by the most seasoned professionals, accidents can occur, and serious injuries or deaths can result. When such accidents are caused by unsafe work environments or faulty equipment, the injured party and his or her family have legal recourse under personal injury law.
Most serious tractor accidents are rollover accidents, in which the tractor either flips onto its side or overturns backward. Some of these accidents occur due to driver error; however, many occur due to unsafe working conditions or defective parts. Tractors are equipped with huge engines and have incredible towing capabilities. Sometimes, employers require their employees to haul loads that overtax the tractors towing capacity; in other cases, they instruct their employees to operate tractors on steep hills or near ditches or other dangerous terrain. In such cases, if there is an accident, rollover or otherwise, employers may be held liable for any resulting injuries or deaths.
Likewise, manufacturers may be held liable if a tractor rolls over due to a design or manufacturing defect or because the tractor was unable to haul a load even though that load weighed less than the maximum weight specified by the manufacturer. In these cases, the injured party and his or her family may be able to recover compensation from the designer, the manufacturer, and/or the marketer of the tractor.
If you have been seriously injured or have lost a loved one in a tractor accident, you may be entitled to compensation for the losses and expenses related to the accident. You would be well advised to contact an experienced personal injury attorney for an evaluation of your potential claim.
Heavy farm and construction equipment is, by nature, dangerous and potentially deadly. This is why such equipment is supposed to be manufactured according to the highest possible safety standards and operated only by trained professionals. However, even when tractors are operated by the most seasoned professionals, accidents can occur, and serious injuries or deaths can result. When such accidents are caused by unsafe work environments or faulty equipment, the injured party and his or her family have legal recourse under personal injury law.
Most serious tractor accidents are rollover accidents, in which the tractor either flips onto its side or overturns backward. Some of these accidents occur due to driver error; however, many occur due to unsafe working conditions or defective parts. Tractors are equipped with huge engines and have incredible towing capabilities. Sometimes, employers require their employees to haul loads that overtax the tractors towing capacity; in other cases, they instruct their employees to operate tractors on steep hills or near ditches or other dangerous terrain. In such cases, if there is an accident, rollover or otherwise, employers may be held liable for any resulting injuries or deaths.
Likewise, manufacturers may be held liable if a tractor rolls over due to a design or manufacturing defect or because the tractor was unable to haul a load even though that load weighed less than the maximum weight specified by the manufacturer. In these cases, the injured party and his or her family may be able to recover compensation from the designer, the manufacturer, and/or the marketer of the tractor.
If you have been seriously injured or have lost a loved one in a tractor accident, you may be entitled to compensation for the losses and expenses related to the accident. You would be well advised to contact an experienced personal injury attorney for an evaluation of your potential claim.
Sunday, August 19, 2012
Tips to Find Affordable Debt Collection Resources in California
Debt collection resources can be a scary topic to many people because it reminds them of nagging creditors. The first thing that happens when you begin defaulting on a loan or credit card installments is that debt collection companies are going to start calling you. These are representatives for the company you are in default with. The Fair liability Collection Practices Act or the FDCPA, was signed into law in the 1970's to protect the public from unfair and unlawful collections activities by third parties, including collections calls, which in many cases are FDCPA violations. A debt collection agency in California holds the added weight and threat of a bad credit rating--something nobody wants--so you'll find that it is often a lot easier for an agent to get results faster. In addition to this, a debt collection service can cater payment plans for clients experiencing financial trouble and the added 'middle man' can take some of the heat out of situations.
Debt collection companies sometimes use bullying tactics and a person's ignorance of the law to try and claim a debt which is not enforceable by law. It can be both worthwhile and profitable to learn How to start a debit Collection Business. With growing consumer liability and therefore a greater need now than ever for debt collectors, this is a great time to break into the field and start on the road to financial independence. The low overhead and start up costs make a debt collection business an ideal choice for people looking to start their own business. These companies play a very important role in resolving differences between the debtors and creditors. The collectors proffer services to creditors and make sure that all their debts are collected within the shortest time possible. They also assist debtors by administering their bills in an organized way.
A debt collection attorney is someone who should be looking after your financial interests. Although the debt can be between you and a family member or someone you have a cordial relationship with, throughout the debt resolution process, it can be difficult to agree on what is fair for both. The person in liability may not have the funds to pay you back. Therefore, this is where a debt collection attorney can be helpful. Debt collection lawyers in California in general are considered in the public eye as having a bad reputation of verbal abuse and are accused of using force to get the money back. This misconception built around the fact that some stories which appear in the press give that impression that this is the case with all the debt collection agencies.
The role of reputable California debt management companies is to help consumers with repayments that have become too large to handle on their own. Unexpected expenses are the most common causes of excess debt, including that incurred from medical emergencies, divorces, or the need to downsize living situations. There are a number of financial options available out there for help with debt. These include things ranging from IVAs and debt consolidation to a debt management plan. Mastering debt management is a necessary aspect of making money work A good place to start on road to Financial Freedom is learning debt management and to begin you have to know the difference between good debt and bad debt.
Get more information on somekeyword with the help of this site. Find best information on somekeyword by visiting this site.
Debt collection companies sometimes use bullying tactics and a person's ignorance of the law to try and claim a debt which is not enforceable by law. It can be both worthwhile and profitable to learn How to start a debit Collection Business. With growing consumer liability and therefore a greater need now than ever for debt collectors, this is a great time to break into the field and start on the road to financial independence. The low overhead and start up costs make a debt collection business an ideal choice for people looking to start their own business. These companies play a very important role in resolving differences between the debtors and creditors. The collectors proffer services to creditors and make sure that all their debts are collected within the shortest time possible. They also assist debtors by administering their bills in an organized way.
A debt collection attorney is someone who should be looking after your financial interests. Although the debt can be between you and a family member or someone you have a cordial relationship with, throughout the debt resolution process, it can be difficult to agree on what is fair for both. The person in liability may not have the funds to pay you back. Therefore, this is where a debt collection attorney can be helpful. Debt collection lawyers in California in general are considered in the public eye as having a bad reputation of verbal abuse and are accused of using force to get the money back. This misconception built around the fact that some stories which appear in the press give that impression that this is the case with all the debt collection agencies.
The role of reputable California debt management companies is to help consumers with repayments that have become too large to handle on their own. Unexpected expenses are the most common causes of excess debt, including that incurred from medical emergencies, divorces, or the need to downsize living situations. There are a number of financial options available out there for help with debt. These include things ranging from IVAs and debt consolidation to a debt management plan. Mastering debt management is a necessary aspect of making money work A good place to start on road to Financial Freedom is learning debt management and to begin you have to know the difference between good debt and bad debt.
Get more information on somekeyword with the help of this site. Find best information on somekeyword by visiting this site.
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